1-Oxo-1-(5,8,9,10-tetrahydro-2H,6H-[1,3]dioxolo[4,5-h]pyrrolo[2,1-b][3]benzazepin-11-yl)propan-2-yl acetate

Base Information

Chemical Name:1-Oxo-1-(5,8,9,10-tetrahydro-2H,6H-[1,3]dioxolo[4,5-h]pyrrolo[2,1-b][3]benzazepin-11-yl)propan-2-yl acetate
CAS No.:38848-22-5
Molecular Formula:C₁₉H₂₁NO₅
Molecular Weight:343.379
Hs Code.:
NSC Number:177246
DSSTox Substance ID:DTXSID90306523

Synonyms:38848-22-5;NSC177246;DTXSID90306523;NSC-177246;1-Oxo-1-(5,8,9,10-tetrahydro-2H,6H-[1,3]dioxolo[4,5-h]pyrrolo[2,1-b][3]benzazepin-11-yl)propan-2-yl acetate

Suppliers and Price of 1-Oxo-1-(5,8,9,10-tetrahydro-2H,6H-[1,3]dioxolo[4,5-h]pyrrolo[2,1-b][3]benzazepin-11-yl)propan-2-yl acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-Oxo-1-(5,8,9,10-tetrahydro-2H,6H-[1,3]dioxolo[4,5-h]pyrrolo[2,1-b][3]benzazepin-11-yl)propan-2-yl acetate

Chemical Property:

Vapor Pressure:4.62E-11mmHg at 25°C
XLogP3:2.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:343.14197277
Heavy Atom Count:25
Complexity:601

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C(=O)C1=C2CCCN2CCC3=CC4=C(C=C31)OCO4)OC(=O)C

Technology Process of 1-Oxo-1-(5,8,9,10-tetrahydro-2H,6H-[1,3]dioxolo[4,5-h]pyrrolo[2,1-b][3]benzazepin-11-yl)propan-2-yl acetate

There total 4 articles about 1-Oxo-1-(5,8,9,10-tetrahydro-2H,6H-[1,3]dioxolo[4,5-h]pyrrolo[2,1-b][3]benzazepin-11-yl)propan-2-yl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 38847-95-9
1-(benzo[1,3]dioxol-5-yl-acetyl)-pyrrolidine-2-carbaldehyde

: 38848-22-5
2-acetoxy-1-(5,8,9,10-tetrahydro-6H-[1,3]dioxolo[4',5':4,5]benzo[1,2-d]pyrrolo[1,2-a]azepin-11-yl)-propan-1-one

Guidance literature:: Multi-step reaction with 3 steps

1: BF₃-Et₂O / CHCl₃

2: (i) LiAlH₄, (ii) H₂O, NaOH

3: NaHCO₃ / acetonitrile

With boron trifluoride diethyl etherate; sodium hydrogencarbonate; In chloroform; acetonitrile;
DOI:10.1021/ja00842a030

Reference yield:

: 38847-96-0
5,8,9,10-tetrahydro-[1,3]dioxolo[4',5':4,5]benzo[d]pyrrolo[1,2-a]azepin-6-one

: 38848-22-5
2-acetoxy-1-(5,8,9,10-tetrahydro-6H-[1,3]dioxolo[4',5':4,5]benzo[1,2-d]pyrrolo[1,2-a]azepin-11-yl)-propan-1-one

Guidance literature:: Multi-step reaction with 2 steps

1: (i) LiAlH₄, (ii) H₂O, NaOH

2: NaHCO₃ / acetonitrile

With sodium hydrogencarbonate; In acetonitrile;
DOI:10.1021/ja00842a030