N-Benzyl-2,2,2-trifluoro-N-(3-oxopropyl)acetamide

Base Information

Chemical Name:N-Benzyl-2,2,2-trifluoro-N-(3-oxopropyl)acetamide
CAS No.:112548-80-8
Molecular Formula:C12H12F3NO2
Molecular Weight:259.228
Hs Code.:
DSSTox Substance ID:DTXSID50553899
Wikidata:Q82434619

Synonyms:N-Benzyl-2,2,2-trifluoro-N-(3-oxopropyl)acetamide;112548-80-8;N-Benzyl-N-(3-oxopropyl)-2,2,2-trifluoroacetamide;SCHEMBL7172779;DTXSID50553899

Suppliers and Price of N-Benzyl-2,2,2-trifluoro-N-(3-oxopropyl)acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of N-Benzyl-2,2,2-trifluoro-N-(3-oxopropyl)acetamide

Chemical Property:

XLogP3:1.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:259.08201311
Heavy Atom Count:18
Complexity:286

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)CN(CCC=O)C(=O)C(F)(F)F

Technology Process of N-Benzyl-2,2,2-trifluoro-N-(3-oxopropyl)acetamide

There total 4 articles about N-Benzyl-2,2,2-trifluoro-N-(3-oxopropyl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 233590-33-5
N-benzyl-N-(but-3-en-1-yl)-2,2,2-trifluoroacetamide

: 112548-80-8
3-(N-benzyltrifluoroacetamido)propionaldehyde

Guidance literature:: With triethanolamine; In pet; 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran;

Reference yield: 68.0%

: 119874-75-8
2-<2-(N-benzyltrifluoroacetamido)ethyl>-1,3-dioxolane

: 112548-80-8
3-(N-benzyltrifluoroacetamido)propionaldehyde

Guidance literature:: With oxalic acid; In tetrahydrofuran; water; for 48h; Heating;
DOI:10.1248/cpb.36.1343

Reference yield:

: 7387-69-1
N-benzyl-2,2,2-trifluoroacetamide

: 112548-80-8
3-(N-benzyltrifluoroacetamido)propionaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: NaH / benzene; dimethylformamide / Heating

2: oxalic acid / tetrahydrofuran; H₂O / Heating

With oxalic acid; sodium hydride; In tetrahydrofuran; water; N,N-dimethyl-formamide; benzene;
DOI:10.1021/ja00211a042