[(1R,2S,3R)-2-((E)-4,8-Dimethyl-nona-3,7-dienyl)-2-methyl-3-((1E,5E)-2,6,10-trimethyl-undeca-1,5,9-trienyl)-cyclopropyl]-methanol

Base Information

• Chemical Name: [(1R,2S,3R)-2-((E)-4,8-Dimethyl-nona-3,7-dienyl)-2-methyl-3-((1E,5E)-2,6,10-trimethyl-undeca-1,5,9-trienyl)-cyclopropyl]-methanol
• CAS No.: 66537-35-7
• Molecular Formula: C₃₀H₅₀O
• Molecular Weight: 426.726
• Mol file: 66537-35-7.mol

Synonyms:

Chemical Property of [(1R,2S,3R)-2-((E)-4,8-Dimethyl-nona-3,7-dienyl)-2-methyl-3-((1E,5E)-2,6,10-trimethyl-undeca-1,5,9-trienyl)-cyclopropyl]-methanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [(1R,2S,3R)-2-((E)-4,8-Dimethyl-nona-3,7-dienyl)-2-methyl-3-((1E,5E)-2,6,10-trimethyl-undeca-1,5,9-trienyl)-cyclopropyl]-methanol

There total 10 articles about [(1R,2S,3R)-2-((E)-4,8-Dimethyl-nona-3,7-dienyl)-2-methyl-3-((1E,5E)-2,6,10-trimethyl-undeca-1,5,9-trienyl)-cyclopropyl]-methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

diphosphoric acid mono-[2t-((E)-4,8-dimethyl-nona-3,7-dienyl)-2c-methyl-3t-((1E,5E)-2,6,10-trimethyl-undeca-1,5,9-trienyl)-cycloprop-r-ylmethyl] ester (29849-75-0,68297-43-8,22477-86-7,30516-84-8) → Despyrophosphoryl-praesqualen (31908-49-3,31908-50-6,31908-51-7,31908-52-8,32205-38-2,32205-47-3,32988-59-3,33669-74-8,56942-03-1,66537-35-7,68297-42-7,117182-28-2) + (6E,10E,16E)-2,6,10,13,17,21-hexamethyl-13-vinyl-docosa-2,6,10,16,20-pentaene (86342-79-2)

Guidance literature:

With lithium aluminium tetrahydride;

DOI:10.1021/ja01032a052

Reference yield:

(1R,2S,3R)-2-((E)-4,8-Dimethyl-nona-3,7-dienyl)-2-methyl-3-((1E,5E)-2,6,10-trimethyl-undeca-1,5,9-trienyl)-cyclopropanecarboxylic acid ethyl ester (31908-53-9,31908-54-0,31908-55-1,31908-56-2,56942-00-8,56942-01-9) → [(1R,2S,3R)-2-((E)-4,8-Dimethyl-nona-3,7-dienyl)-2-methyl-3-((1E,5E)-2,6,10-trimethyl-undeca-1,5,9-trienyl)-cyclopropyl]-methanol (31908-49-3,31908-50-6,31908-51-7,31908-52-8,32205-38-2,32205-47-3,32988-59-3,33669-74-8,56942-03-1,66537-35-7,68297-42-7,117182-28-2)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether;

DOI:10.1039/P19750000897

Reference yield:

farnesol (4602-84-0) → [(1R,2S,3R)-2-((E)-4,8-Dimethyl-nona-3,7-dienyl)-2-methyl-3-((1E,5E)-2,6,10-trimethyl-undeca-1,5,9-trienyl)-cyclopropyl]-methanol (31908-49-3,31908-50-6,31908-51-7,31908-52-8,32205-38-2,32205-47-3,32988-59-3,33669-74-8,56942-03-1,66537-35-7,68297-42-7,117182-28-2)

Guidance literature:

Multi-step reaction with 4 steps

1: PBr₃, Py / diethyl ether

2: methanol

3: KOtBu / dimethylformamide

4: LiAlH₄ / diethyl ether

With pyridine; lithium aluminium tetrahydride; potassium tert-butylate; phosphorus tribromide; In methanol; diethyl ether; N,N-dimethyl-formamide;

DOI:10.1039/P19750000897

upstream raw materials:

diphosphoric acid mono-[2t-((E)-4,8-dimethyl-nona-3,7-dienyl)-2c-methyl-3t-((1E,5E)-2,6,10-trimethyl-undeca-1,5,9-trienyl)-cycloprop-r-ylmethyl] ester

(1R,2S,3R)-2-((E)-4,8-Dimethyl-nona-3,7-dienyl)-2-methyl-3-((1E,5E)-2,6,10-trimethyl-undeca-1,5,9-trienyl)-cyclopropanecarboxylic acid ethyl ester

farnesol

farnesyl bromide