(R)-1-(4-Trifluoromethylphenyl)-1-propanol

Base Information

Chemical Name:(R)-1-(4-Trifluoromethylphenyl)-1-propanol
CAS No.:112777-69-2
Molecular Formula:C₁₀H₁₁F₃O
Molecular Weight:204.192
Hs Code.:2906290090
DSSTox Substance ID:DTXSID50436537
Nikkaji Number:J1.327.256E
Wikidata:Q82251816
Mol file:112777-69-2.mol

Synonyms:112777-69-2;(R)-1-(4-Trifluoromethylphenyl)-1-propanol;(R)-1-(4-(trifluoromethyl)phenyl)propan-1-ol;(1R)-1-[4-(trifluoromethyl)phenyl]propan-1-ol;(R)-1-(4-(Trifluoromethyl)phenyl)-1-propanol;(R)-1-[4-(Trifluoromethyl)phenyl]-1-propanol;SCHEMBL10073359;DTXSID50436537;AKOS025311262;AT33168;(1R)-1-[4-(Trifluoromethyl)phenyl]-1-propanol;(1R)-(+)-1-[4-(Trifluoromethyl)phenyl]propan-1-ol 97%

Suppliers and Price of (R)-1-(4-Trifluoromethylphenyl)-1-propanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
(R)-1-[4-(Trifluoromethyl)phenyl]propan-1-ol 97%
1 g
$ 495.00

SynQuest Laboratories
(R)-1-[4-(Trifluoromethyl)phenyl]propan-1-ol 97%
250 mg
$ 155.00

American Custom Chemicals Corporation
(R)-1-(4-TRIFLUOROMETHYL PHENYL)-1-PROPANOL 95.00%
1G
$ 1033.73

Total 18 raw suppliers

Chemical Property of (R)-1-(4-Trifluoromethylphenyl)-1-propanol

Chemical Property:

Boiling Point:234.8±35.0 °C(Predicted)
PKA:13.98±0.20(Predicted)
PSA：20.23000
Density:1?+-.0.06 g/cm3(Predicted)
LogP:3.14880
XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:204.07619946
Heavy Atom Count:14
Complexity:171

Purity/Quality:

99% ^*data from raw suppliers

(R)-1-[4-(Trifluoromethyl)phenyl]propan-1-ol 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC(C1=CC=C(C=C1)C(F)(F)F)O
Isomeric SMILES:CC[C@H](C1=CC=C(C=C1)C(F)(F)F)O

Technology Process of (R)-1-(4-Trifluoromethylphenyl)-1-propanol

There total 24 articles about (R)-1-(4-Trifluoromethylphenyl)-1-propanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 455-19-6
4-Trifluoromethylbenzaldehyde

: 557-20-0
diethylzinc

: 67081-98-5,73854-05-4,112777-69-2
(R)-1-(4-(trifluoromethyl)phenyl)propan-1-ol

Guidance literature:: 4-Trifluoromethylbenzaldehyde; diethylzinc; With (2R,3S,3aS,4aR,6R,8aS)-2-isopropyl-6,9,9-trimethyl-3-phenyldecahydro-4aH-pyrrolo[2,1-b][1,3]benzoxazin-3-ol; In hexane; toluene; at 20 ℃; Inert atmosphere;

With ammonium chloride; In hexane; water; toluene; optical yield given as %ee; enantioselective reaction;
DOI:10.1016/j.tetasy.2010.07.016

Reference yield: 99.0%

: 455-19-6
4-Trifluoromethylbenzaldehyde

: 557-20-0
diethylzinc

: 67081-98-5,112777-69-2,73854-05-4
(S)-1-(4-(trifluoromethyl)phenyl)propan-1-ol

: 67081-98-5,73854-05-4,112777-69-2
(R)-1-(4-(trifluoromethyl)phenyl)propan-1-ol

Guidance literature:: With 4-methyl-N-{[(1S,2S)-2-(pyrrolidin-1-yl)cyclohexyl]methyl}benzenesulfonamide; In hexane; at 0 ℃; for 24h; optical yield given as %ee; enantioselective reaction; Inert atmosphere;
DOI:10.1021/jo200834n

Reference yield: 99.0%

: 455-19-6
4-Trifluoromethylbenzaldehyde

: 557-20-0
diethylzinc

: 67081-98-5,112777-69-2,73854-05-4
(S)-1-(4-(trifluoromethyl)phenyl)propan-1-ol

: 67081-98-5,73854-05-4,112777-69-2
(R)-1-(4-(trifluoromethyl)phenyl)propan-1-ol

Guidance literature:: With 4-methyl-N-{[(1S,2S)-2-(pyrrolidin-1-yl)cyclohexyl]methyl}benzenesulfonamide; In hexane; at 0 ℃; for 24h; optical yield given as %ee; enantioselective reaction; Inert atmosphere;
DOI:10.1021/jo200834n