Technology Process of C32H46FN3O5
There total 4 articles about C32H46FN3O5 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
palladium 10% on activated carbon; hydrogen;
In
methanol;
at 20 ℃;
for 12h;
DOI:10.1021/ja302269r
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: Dess-Martin periodane / dichloromethane / 18 h / 20 °C / Inert atmosphere
2.1: lithium hexamethyldisilazane / tetrahydrofuran / 1 h / -78 - 0 °C / Inert atmosphere
2.2: 8 h / -78 - 20 °C / Inert atmosphere
3.1: palladium 10% on activated carbon; hydrogen / methanol / 12 h / 20 °C
With
palladium 10% on activated carbon; hydrogen; Dess-Martin periodane; lithium hexamethyldisilazane;
In
tetrahydrofuran; methanol; dichloromethane;
2.2: Wittig reaction;
DOI:10.1021/ja302269r
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: 20% palladium hydroxide-activated charcoal; hydrogen / ethanol / 36 h / 60 °C
2.1: Dess-Martin periodane / dichloromethane / 18 h / 20 °C / Inert atmosphere
3.1: lithium hexamethyldisilazane / tetrahydrofuran / 1 h / -78 - 0 °C / Inert atmosphere
3.2: 8 h / -78 - 20 °C / Inert atmosphere
4.1: palladium 10% on activated carbon; hydrogen / methanol / 12 h / 20 °C
With
palladium 10% on activated carbon; 20% palladium hydroxide-activated charcoal; hydrogen; Dess-Martin periodane; lithium hexamethyldisilazane;
In
tetrahydrofuran; methanol; ethanol; dichloromethane;
3.2: Wittig reaction;
DOI:10.1021/ja302269r
