C₂₀H₁₇F₃N₄O₂

Base Information

Chemical Name:C₂₀H₁₇F₃N₄O₂
CAS No.:1620328-07-5
Molecular Formula:C₂₀H₁₇F₃N₄O₂
Molecular Weight:402.376
Hs Code.:

C<sub>20</sub>H<sub>17</sub>F<sub>3</sub>N<sub>4</sub>O<sub>2</sub>

Synonyms:

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Chemical Property of C₂₀H₁₇F₃N₄O₂

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Technology Process of C₂₀H₁₇F₃N₄O₂

There total 14 articles about C₂₀H₁₇F₃N₄O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1629023-87-5
C₄₂H₃₅F₃N₄O₂

: 1620328-07-5
C₂₀H₁₇F₃N₄O₂

Guidance literature:: With N-tris(hydroxymethyl)methyl-2-aminoethanesulfonic acid; trifluoroacetic acid; In dichloromethane; at 0 ℃; for 2h;
DOI:10.1016/j.bmcl.2014.05.082

Reference yield:

: 1160502-31-7
4-iodo-3-(trifluoromethyl)-1-tritylpyrazolo[5,4-b]pyridine

: 1620328-07-5
C₂₀H₁₇F₃N₄O₂

Guidance literature:: Multi-step reaction with 3 steps

1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate / N,N-dimethyl-formamide / 14 h / 105 °C

2: potassium phosphate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; tri tert-butylphosphoniumtetrafluoroborate / tetrahydrofuran; water / 2.5 h / 20 °C

3: N-tris(hydroxymethyl)methyl-2-aminoethanesulfonic acid; trifluoroacetic acid / dichloromethane / 2 h / 0 °C

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium phosphate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; N-tris(hydroxymethyl)methyl-2-aminoethanesulfonic acid; potassium acetate; trifluoroacetic acid; tri tert-butylphosphoniumtetrafluoroborate; In tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide; 1: |Suzuki Coupling / 2: |Suzuki Coupling;
DOI:10.1016/j.bmcl.2014.05.082

Reference yield:

: 1620327-60-7
C₃₂H₂₉BF₃N₃O₂

: 1620328-07-5
C₂₀H₁₇F₃N₄O₂

Guidance literature:: Multi-step reaction with 2 steps

1: potassium phosphate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; tri tert-butylphosphoniumtetrafluoroborate / tetrahydrofuran; water / 2.5 h / 20 °C

2: N-tris(hydroxymethyl)methyl-2-aminoethanesulfonic acid; trifluoroacetic acid / dichloromethane / 2 h / 0 °C

With potassium phosphate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; N-tris(hydroxymethyl)methyl-2-aminoethanesulfonic acid; trifluoroacetic acid; tri tert-butylphosphoniumtetrafluoroborate; In tetrahydrofuran; dichloromethane; water; 1: |Suzuki Coupling;
DOI:10.1016/j.bmcl.2014.05.082