7-pentyl-3-(4-propylphenyl)-3,4-dihydro-1(2H)-naphthalenone

Base Information

• Chemical Name: 7-pentyl-3-(4-propylphenyl)-3,4-dihydro-1(2H)-naphthalenone
• CAS No.: 83787-75-1
• Molecular Formula: C₂₄H₃₀O
• Molecular Weight: 334.502
• Mol file: 83787-75-1.mol

Synonyms:

Chemical Property of 7-pentyl-3-(4-propylphenyl)-3,4-dihydro-1(2H)-naphthalenone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 7-pentyl-3-(4-propylphenyl)-3,4-dihydro-1(2H)-naphthalenone

There total 6 articles about 7-pentyl-3-(4-propylphenyl)-3,4-dihydro-1(2H)-naphthalenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-(4-Pentyl-phenyl)-3-(4-propyl-phenyl)-butyryl chloride → 7-pentyl-3-(4-propylphenyl)-3,4-dihydro-1(2H)-naphthalenone (83787-75-1)

Guidance literature:

With aluminium trichloride; In dichloromethane; at -50 ℃; for 2h; Yield given;

DOI:10.1002/hlca.19820650423

Reference yield:

4-pentylbenzyl 4-propylphenyl ketone (83805-09-8) → 7-pentyl-3-(4-propylphenyl)-3,4-dihydro-1(2H)-naphthalenone (83787-75-1)

Guidance literature:

Multi-step reaction with 6 steps

1: 95 percent / Zn / benzene / 2.5 h / 70 - 75 °C

2: 70percent aq. HClO₄ / acetic acid / 0.17 h / 50 °C / vacuum

3: H₂ / 10percent Pd/C / ethanol / 2 h / Ambient temperature

4: NaOH / H₂O; CH₂Cl₂; methanol / 1.) 50 deg C, 1 h; 2.) 57 deg C, 2 h

5: SOCl₂ / dimethylformamide; toluene / Ambient temperature

6: AlCl₃ / CH₂Cl₂ / 2 h / -50 °C

With sodium hydroxide; aluminium trichloride; thionyl chloride; perchloric acid; hydrogen; zinc; palladium on activated charcoal; In methanol; ethanol; dichloromethane; water; acetic acid; N,N-dimethyl-formamide; toluene; benzene;

DOI:10.1002/hlca.19820650423

Reference yield:

(E)-4-(4-Pentyl-phenyl)-3-(4-propyl-phenyl)-but-3-enoic acid ethyl ester → 7-pentyl-3-(4-propylphenyl)-3,4-dihydro-1(2H)-naphthalenone (83787-75-1)

Guidance literature:

Multi-step reaction with 4 steps

1: H₂ / 10percent Pd/C / ethanol / 2 h / Ambient temperature

2: NaOH / H₂O; CH₂Cl₂; methanol / 1.) 50 deg C, 1 h; 2.) 57 deg C, 2 h

3: SOCl₂ / dimethylformamide; toluene / Ambient temperature

4: AlCl₃ / CH₂Cl₂ / 2 h / -50 °C

With sodium hydroxide; aluminium trichloride; thionyl chloride; hydrogen; palladium on activated charcoal; In methanol; ethanol; dichloromethane; water; N,N-dimethyl-formamide; toluene;

DOI:10.1002/hlca.19820650423

upstream raw materials:

4-pentylbenzyl 4-propylphenyl ketone

4-(4-pentylphenyl)-3-(4-propylphenyl)butyric acid

ethyl 4-(4-pentylphenyl)-3-(4-propylphenyl)butyrate

ethyl 3-hydroxy-4-(4-pentylphenyl)-3-(4-propylphenyl)butyrate

Refernces