2-Phenyl-3,4-dihydro-2h-1,4-benzoxazine

Base Information

Chemical Name:2-Phenyl-3,4-dihydro-2h-1,4-benzoxazine
CAS No.:113342-87-3
Molecular Formula:C14H13NO
Molecular Weight:211.263
Hs Code.:
DSSTox Substance ID:DTXSID30549513
Nikkaji Number:J1.875.136D
Mol file:113342-87-3.mol

Synonyms:2-phenyl-3,4-dihydro-2h-1,4-benzoxazine;113342-87-3;SCHEMBL9177187;DTXSID30549513;RBSBKTPCGIYIBX-UHFFFAOYSA-N;AKOS018979914;3,4-dihydro-2-phenyl-2H-1,4-benzoxazine

Suppliers and Price of 2-Phenyl-3,4-dihydro-2h-1,4-benzoxazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-Phenyl-3,4-dihydro-2h-1,4-benzoxazine

Chemical Property:

XLogP3:3.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:211.099714038
Heavy Atom Count:16
Complexity:225

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(OC2=CC=CC=C2N1)C3=CC=CC=C3

Technology Process of 2-Phenyl-3,4-dihydro-2h-1,4-benzoxazine

There total 8 articles about 2-Phenyl-3,4-dihydro-2h-1,4-benzoxazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 501419-65-4
2-phenyl-4-(toluene-4-sulfonyl)-3,4-dihydro-2H-1,4-benzoxazine

: 113342-87-3
2-phenyl-3,4-dihydro-2H-benzo[b][1,4]oxazine

Guidance literature:: With magnesium; In methanol; at 20 ℃; for 1h; Inert atmosphere;
DOI:10.1021/acs.joc.8b00788

Reference yield: 52.0%

: 30914-95-5
2-phenyl-2H-benzo[b][1,4]oxazin-3(4H)-one

: 113342-87-3
2-phenyl-3,4-dihydro-2H-benzo[b][1,4]oxazine

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; 0 deg C, reflux, 24 h;

Reference yield:

: 37167-62-7,3042-81-7,61139-20-6
bromo-phenyl-acetic acid methyl ester

: 113342-87-3
2-phenyl-3,4-dihydro-2H-benzo[b][1,4]oxazine

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) potassium iodide, anhydrous potassium carbonate; 2.) sodium methoxyde / 1.) acetone, reflux, 12 h; 2.) benzene, reflux, 7 h

2: 52 percent / lithium aluminium hydride / tetrahydrofuran / 0 deg C, reflux, 24 h

With lithium aluminium tetrahydride; sodium methylate; potassium carbonate; potassium iodide; In tetrahydrofuran;