1-(4-Benzyloxy-phenyl)-4-octyloxy-cyclohexanol

Base Information

• Chemical Name: 1-(4-Benzyloxy-phenyl)-4-octyloxy-cyclohexanol
• CAS No.: 155171-63-4
• Molecular Formula: C₂₇H₃₈O₃
• Molecular Weight: 410.597
• Mol file: 155171-63-4.mol

Synonyms:

Chemical Property of 1-(4-Benzyloxy-phenyl)-4-octyloxy-cyclohexanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(4-Benzyloxy-phenyl)-4-octyloxy-cyclohexanol

There total 5 articles about 1-(4-Benzyloxy-phenyl)-4-octyloxy-cyclohexanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-bromo-octane (111-83-1) → 1-(4-Benzyloxy-phenyl)-4-octyloxy-cyclohexanol (155171-63-4)

Guidance literature:

Multi-step reaction with 4 steps

1: 1.) NaOEt, 2.) KI / 1.) EtOH, 2.) EtOH

2: 93 percent / H₂ / Raney nickel / 7 h / 160 °C / 136800 Torr

3: 95 percent / pyridinium dichromate, CF₃CO₂H, pyridine / CH₂Cl₂ / 3 h / Ambient temperature

4: 1.) Mg, 2.) aq. NH₄Cl

With pyridine; dipyridinium dichromate; hydrogen; sodium ethanolate; ammonium chloride; magnesium; trifluoroacetic acid; potassium iodide; nickel; In dichloromethane;

DOI:10.1039/c39940000365

Reference yield:

1-(benzyloxy)-4-(octyloxy)benzene (67399-80-8) → 1-(4-Benzyloxy-phenyl)-4-octyloxy-cyclohexanol (155171-63-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 93 percent / H₂ / Raney nickel / 7 h / 160 °C / 136800 Torr

2: 95 percent / pyridinium dichromate, CF₃CO₂H, pyridine / CH₂Cl₂ / 3 h / Ambient temperature

3: 1.) Mg, 2.) aq. NH₄Cl

With pyridine; dipyridinium dichromate; hydrogen; ammonium chloride; magnesium; trifluoroacetic acid; nickel; In dichloromethane;

DOI:10.1039/c39940000365

Reference yield:

4-Benzyloxyphenol (103-16-2) → 1-(4-Benzyloxy-phenyl)-4-octyloxy-cyclohexanol (155171-63-4)

Guidance literature:

Multi-step reaction with 4 steps

1: 1.) NaOEt, 2.) KI / 1.) EtOH, 2.) EtOH

2: 93 percent / H₂ / Raney nickel / 7 h / 160 °C / 136800 Torr

3: 95 percent / pyridinium dichromate, CF₃CO₂H, pyridine / CH₂Cl₂ / 3 h / Ambient temperature

4: 1.) Mg, 2.) aq. NH₄Cl

With pyridine; dipyridinium dichromate; hydrogen; sodium ethanolate; ammonium chloride; magnesium; trifluoroacetic acid; potassium iodide; nickel; In dichloromethane;

DOI:10.1039/c39940000365

upstream raw materials:

p-benzyloxyphenylbromide

4-n-Octyloxycyclohexanone

1-bromo-octane

1-(benzyloxy)-4-(octyloxy)benzene

Downstream raw materials:

4-(4-Octyloxy-cyclohexyl)-phenol