1-benzyl-N,N-dimethyl-4-(3-(2-(pyridin-4-yl)ethyl)-1H-indol-2-yl)cyclohexanamine citrate

Base Information

• Chemical Name: 1-benzyl-N,N-dimethyl-4-(3-(2-(pyridin-4-yl)ethyl)-1H-indol-2-yl)cyclohexanamine citrate
• CAS No.: 1004543-96-7
• Molecular Formula: C₆H₈O₇*C₃₀H₃₅N₃
• Molecular Weight: 629.753
• Mol file: 1004543-96-7.mol

Synonyms:

Chemical Property of 1-benzyl-N,N-dimethyl-4-(3-(2-(pyridin-4-yl)ethyl)-1H-indol-2-yl)cyclohexanamine citrate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-benzyl-N,N-dimethyl-4-(3-(2-(pyridin-4-yl)ethyl)-1H-indol-2-yl)cyclohexanamine citrate

There total 4 articles about 1-benzyl-N,N-dimethyl-4-(3-(2-(pyridin-4-yl)ethyl)-1H-indol-2-yl)cyclohexanamine citrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-benzyl-N,N-dimethyl-4-(3-(2-(pyridin-4-yl)ethyl)-1H-indol-2-yl)cyclohexanamine (1004543-95-6) + citric acid (77-92-9,906507-37-7) → 1-benzyl-N,N-dimethyl-4-(3-(2-(pyridin-4-yl)ethyl)-1H-indol-2-yl)cyclohexanamine citrate (1004543-96-7)

Guidance literature:

In methanol; chloroform;

Reference yield:

4-benzyl-4-(dimethylamino)cyclohexanone (475098-34-1) → 1-benzyl-N,N-dimethyl-4-(3-(2-(pyridin-4-yl)ethyl)-1H-indol-2-yl)cyclohexanamine citrate (1004543-96-7)

Guidance literature:

Multi-step reaction with 3 steps

1.1: trifluorormethanesulfonic acid / dichloromethane / 67 h / 20 °C

1.2: 1 h

2.1: hydrogen / 5%-palladium/activated carbon / methanol / 3 h / 20 °C / 2250.23 Torr / Inert atmosphere

3.1: methanol; chloroform

With trifluorormethanesulfonic acid; hydrogen; 5%-palladium/activated carbon; In methanol; dichloromethane; chloroform;

Reference yield:

3-(2-pyridin-4-yl-ethyl)-indole (16571-49-6) → 1-benzyl-N,N-dimethyl-4-(3-(2-(pyridin-4-yl)ethyl)-1H-indol-2-yl)cyclohexanamine citrate (1004543-96-7)

Guidance literature:

Multi-step reaction with 3 steps

1.1: trifluorormethanesulfonic acid / dichloromethane / 67 h / 20 °C

1.2: 1 h

2.1: hydrogen / 5%-palladium/activated carbon / methanol / 3 h / 20 °C / 2250.23 Torr / Inert atmosphere

3.1: methanol; chloroform

With trifluorormethanesulfonic acid; hydrogen; 5%-palladium/activated carbon; In methanol; dichloromethane; chloroform;

upstream raw materials:

1-benzyl-N,N-dimethyl-4-(3-(2-(pyridin-4-yl)ethyl)-1H-indol-2-yl)cyclohexanamine

citric acid

4-benzyl-4-(dimethylamino)cyclohexanone

3-(2-pyridin-4-yl-ethyl)-indole