(R)-1,2,3,4-tetrahydro-1-naphthyl acetate

Base Information

• Chemical Name: (R)-1,2,3,4-tetrahydro-1-naphthyl acetate
• CAS No.: 65915-64-2
• Molecular Formula: C₁₂H₁₄O₂
• Molecular Weight: 190.242
• Mol file: 65915-64-2.mol

Synonyms:

Chemical Property of (R)-1,2,3,4-tetrahydro-1-naphthyl acetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (R)-1,2,3,4-tetrahydro-1-naphthyl acetate

There total 14 articles about (R)-1,2,3,4-tetrahydro-1-naphthyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

tetralin (119-64-2) + acetic acid (64-19-7,77671-22-8) → 1,2,3,4-tetrahydronaphthalen-1-yl acetate (23357-51-9,65915-64-2,79465-04-6,21503-12-8) + 3,4-dihydronaphthalene-1(2H)-one (529-34-0)

Guidance literature:

With C₂₆H₂₈F₆MnN₆O₇S₂; dihydrogen peroxide; In water; acetonitrile; at 20 ℃; for 0.5h; Inert atmosphere;

DOI:10.1021/ol4037083

Reference yield: 48.0%

vinyl acetate (108-05-4,9003-20-7) + 1,2,3,4-Tetrahydro-1-naphthol (529-33-9) → (S)-1-tetralol (53732-47-1) + (R)-1,2,3,4-tetrahydro-1-naphthyl acetate (21503-12-8,65915-64-2,79465-04-6,23357-51-9)

Guidance literature:

With Candida antarctica lipase B; In hexane; at 32 ℃; for 2.3h;

DOI:10.1016/j.tetasy.2007.05.007

Reference yield: 40.0%

vinyl acetate (108-05-4,9003-20-7) + 1,2,3,4-Tetrahydro-1-naphthol (529-33-9) → (S)-1-tetralol (53732-47-1) + (R)-1,2,3,4-tetrahydro-1-naphthyl acetate (21503-12-8,65915-64-2,79465-04-6,23357-51-9) + (R)-1-tetralol (23357-45-1)

Guidance literature:

With lipase Amano PS₃₀; In various solvent(s); Enzymatic reaction;

DOI:10.1021/jo001414d

upstream raw materials:

tetralin

sodium acetate

naphthalene

acetic anhydride

Downstream raw materials:

1,2-Dihydronaphthalene

2-Hydroxy-2-(1,2,3,4-tetrahydro-1-naphthyl)-1-cyclohexanon

(S)-(-)-1,2,3,4-tetrahydronaphthalen-1-yl acetate

(S)-1-tetralol