1-Brom-4-(2,4,10-trioxatricyclo<3.3.1.1^3,7>dec-3-yl)hexan

Base Information

• Chemical Name: 1-Brom-4-(2,4,10-trioxatricyclo<3.3.1.1^3,7>dec-3-yl)hexan
• CAS No.: 88784-99-0
• Molecular Formula: C₁₃H₂₁BrO₃
• Molecular Weight: 305.212
• Mol file: 88784-99-0.mol

Synonyms:

Chemical Property of 1-Brom-4-(2,4,10-trioxatricyclo<3.3.1.1^3,7>dec-3-yl)hexan

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-Brom-4-(2,4,10-trioxatricyclo<3.3.1.1^3,7>dec-3-yl)hexan

There total 1 articles about 1-Brom-4-(2,4,10-trioxatricyclo<3.3.1.1^3,7>dec-3-yl)hexan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,3,5-cyclohexanetriol (2041-15-8,13314-30-2) + 7-Bromo-1,1,1-trimethoxy-heptane → methyl 7-bromoheptanoate (54049-24-0) + 1-Brom-4-(2,4,10-trioxatricyclo<3.3.1.13,7>dec-3-yl)hexan (88784-99-0)

Guidance literature:

With boron trifluoride diethyl etherate; In methanol; for 2h; Yield given. Yields of byproduct given;

DOI:10.1002/hlca.19830660741

Reference yield:

1-Brom-4-(2,4,10-trioxatricyclo<3.3.1.13,7>dec-3-yl)hexan (88784-99-0) → (R)-9-Hydroxydecansaeure-(3,5-dihydroxy-1-cyclohexyl)ester

Guidance literature:

Multi-step reaction with 2 steps

1: 1) Mg, 2) COD*CuCl / 1) THF, 1,2-dibromoethan, reflux, 4 h, 2) THF, 35 deg C, 20 min

2: 0.02N H₂SO₄ / ethyl acetate; dioxane / 1 h / Heating

With COD*CuCl; sulfuric acid; magnesium; In 1,4-dioxane; ethyl acetate;

DOI:10.1002/hlca.19830660741

Reference yield:

1-Brom-4-(2,4,10-trioxatricyclo<3.3.1.13,7>dec-3-yl)hexan (88784-99-0) → (+)-(S)-9-Hydroxydecansaeure (35433-72-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 1) Mg, 2) COD*CuCl / 1) THF, 1,2-dibromoethan, reflux, 4 h, 2) THF, 35 deg C, 20 min

2: 1) 0.02N H₂SO₄; 2) 2N KOH / ethyl acetate; dioxane / 1) reflux, 30 min; 2) reflux, 30 min

With potassium hydroxide; COD*CuCl; sulfuric acid; magnesium; In 1,4-dioxane; ethyl acetate;

DOI:10.1002/hlca.19830660741

upstream raw materials:

1,3,5-cyclohexanetriol

Downstream raw materials:

(+)-(S)-9-Hydroxydecansaeure

(R)-9-hydroxydecanoic acid