35433-72-8

Basic information

• Product Name: (S)-9-Hydroxydecanoic acid
• Synonyms: (S)-9-Hydroxydecanoic acid;L-9-Hydroxycapric acid;L-9-Hydroxydecanoic acid
• CAS NO: 35433-72-8
• Molecular Formula: C10H20O3
• Molecular Weight: 0
• Mol File: 35433-72-8.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (S)-9-Hydroxydecanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-9-Hydroxydecanoic acid(35433-72-8)
• EPA Substance Registry System: (S)-9-Hydroxydecanoic acid(35433-72-8)

Safety Data

• Hazardous Substances Data: 35433-72-8(Hazardous Substances Data)

Upstream product

• 69008-87-3 2-decen-9-olide (E isomer) 
• 88784-99-0 1-Brom-4-(2,4,10-trioxatricyclo<3.3.1.1^3,7>dec-3-yl)hexan 
• 20965-27-9 7-bromo-heptanonitrile 
• 629-03-8 1 ,6-dibromohexane 
• 157730-85-3 (R)-(+)-9-trityloxy-2-decanol 
• 157730-86-4 1-trityloxy-9-t-butyldimethylsilyloxydecane 
• 157730-87-5 9-t-butyldimethylsilyloxy-1-decanol 
• 157730-88-6 (S)-9-(tert-Butyl-dimethyl-silanyloxy)-decanoic acid 
• 88785-11-9 (+)-(S)-9-(2,4,10-Trioxatricyclo<3.3.1.1^3,7>dec-3-yl)-2-nonanol 
• 1422-26-0 9-oxodecanoic acid 

Downstream Products

• 61448-27-9 (S)-(+)-phoracantholide I 
• 61448-27-9 (R)-(-)-phoracantholide I 

Relevant articles and documents

Catalytic enantioselective macrolide synthesis II: Use of differential deprotection protocols

Catalytic enantioselective synthesis of Phorcantholide I has been achieved. Key stereochemistry was introduced using a chiral arene chromium tricarbonyl based catalyst to mediate the addition of dimethyl zinc to a functionalised aldehyde. During the synth

Synthesis of Both the Enantiomers of Phoracantholide I; A Defensive Secretion of the Eucarypt Longicorn (Phoracantha synonyma), Employing Microbial Asymmetric Reduction with Immobilized Baker's Yeast

Highly optically pure (R)- and (S)-phoracantholide I were synthesized in relatively short steps starting from diethyl 3-oxoglutarate by means of a microbial asymmetric reduction of the intermediate keto acid with immobilized baker's yeast entrapped in gels of κ-carrageenan.

Orthocarbonsaeure-ester mit 2,4,10-Trioxaadamantanstruktur als Carboxylschutzgruppe; Verwendung zur Synthese von substituierten Carbonsaeuren mit Hilfe von Grignard-Reagenzien

The surprising stability of 2,4,10-trioxa-3-adamantyl derivatives 1 against nucleophilic substitution by organomagnesium compounds is discussed and shown to be caused by unfavourable stereoelectronic and steric factors governing the substitution of these cage compounds (Scheme 2).As a consequence, a number of Grignard reagents 2 containing the carboxyl group masked as 2,4,10-trioxa-3-adamantyl group could be prepared and have been reacted in a second step with various electrophiles (cf.Scheme 4).In the products 7-13 and 15b the carboxyl masking group is removed by mild ac id hydrolysis and saponification (cf.Scheme 3) to yield the corresponding acids 16a-21a, 22, and 23a.Acids 21a and 23a have been further transformed to give the macrocyclic lactones 24 and 26, isolated from Galbanum oleo-gum-resin, and acid 22 to give 12-methyl-13-tridecanolide (25), isolated from Angelica root oil.In addition 1-bromo-ω-(2,4,10-trioxa-3-adamantyl)alkanes 1c and 1b have been used to synthesize (+/-)-methyl recifeiolate (29b) and pure cis-ambrettolic acid ((Z)-32a).