Technology Process of 2-Pyrrolidinone, 1-hydroxy-4-methyl-5,5-bis(phenylmethyl)-
There total 5 articles about 2-Pyrrolidinone, 1-hydroxy-4-methyl-5,5-bis(phenylmethyl)- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
zinc;
In
acetic acid;
1.) r.t., 20 min; 2.) 100 deg C, 3 h;
DOI:10.1039/P19870002027
- Guidance literature:
-
Multi-step reaction with 4 steps
1: MeNH2*HCl, AcOK, trimethyl orthoformate / methanol / 16 h / Heating
2: NaBH4 / dimethylsulfoxide / 1 h / 20 °C
3: 63.4 percent / tetrabutylammonium chloride, KF*2H2O / dimethylformamide / 50 h / 60 °C
4: 82.1 percent / Zn powder / acetic acid / 1.) r.t., 20 min; 2.) 100 deg C, 3 h
With
potassium fluoride; sodium tetrahydroborate; tetrabutyl-ammonium chloride; methylamine hydrochloride; potassium acetate; zinc; trimethyl orthoformate;
In
methanol; acetic acid; dimethyl sulfoxide; N,N-dimethyl-formamide;
DOI:10.1039/P19870002027
- Guidance literature:
-
Multi-step reaction with 3 steps
1: NaBH4 / dimethylsulfoxide / 1 h / 20 °C
2: 63.4 percent / tetrabutylammonium chloride, KF*2H2O / dimethylformamide / 50 h / 60 °C
3: 82.1 percent / Zn powder / acetic acid / 1.) r.t., 20 min; 2.) 100 deg C, 3 h
With
potassium fluoride; sodium tetrahydroborate; tetrabutyl-ammonium chloride; zinc;
In
acetic acid; dimethyl sulfoxide; N,N-dimethyl-formamide;
DOI:10.1039/P19870002027
