3-phenyl-3-germatranylpropionic acid

Base Information

• Chemical Name: 3-phenyl-3-germatranylpropionic acid
• CAS No.: 106015-60-5
• Molecular Formula: C₁₅H₂₁GeNO₅
• Molecular Weight: 367.925
• Mol file: 106015-60-5.mol

Synonyms:

Chemical Property of 3-phenyl-3-germatranylpropionic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-phenyl-3-germatranylpropionic acid

There total 1 articles about 3-phenyl-3-germatranylpropionic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

triethanolamine (102-71-6,64114-46-1) + 3-phenyl-3-germaniumsesquioxidepropionic acid → 3-phenyl-3-germatranylpropionic acid (106015-60-5)

Guidance literature:

In toluene; byproducts: H2O; under Ar, (HOCH2CH2)3N was added dropwise to toluene soln. of Ge-compd.,reflux for 6 h with constant removal of water; toluene was decanted, crystn. from 95 % hot EtOH, elem. anal.;

DOI:10.1081/SIM-100002047

Reference yield: 93.5%

dibutyltin(IV) oxide + 3-phenyl-3-germatranylpropionic acid (106015-60-5) → (CH3(CH2)3)2Sn(O2CCH2CH(C6H5)Ge((OCH2CH2)3N))2(H2O) (214913-04-9)

Guidance literature:

In toluene; refluxing Sn-compd. with 2 equiv. of Ge-compd. for 6 h; concn. (distn.), filtration, evapn. (vac.), recrystn. (CHCl3/petroleum ether); elem. anal.;

DOI:10.1016/S0022-328X(98)00607-X

Reference yield: 80.0%

3-phenyl-3-germatranylpropionic acid (106015-60-5) + bis((trimethylsilyl)methyl)tin dichloride (38047-49-3) → bis(trimethylsilylmethyl)bis(3-phenyl-3-germatranyl)tin(IV) propionate (355018-20-1)

Guidance literature:

In ethanol; under Ar, Ge-compd. was added to mixt. of Sn-compd. and Et3N in EtOH, reflux for 6 h; soln. was cooled, EtOH was removed in vac., solid was extd. with CH2Cl2,elem. anal.;

DOI:10.1081/SIM-100002047

upstream raw materials:

triethanolamine

Downstream raw materials:

tris(neopentyl)-(3-phenyl-3-germatranyl)tin(IV) propionate

bis(ethyldimethylsilylmethyl)bis(3-phenyl-3-germatranyl)tin(IV) propionate

bis(trimethylsilylmethyl)bis(3-phenyl-3-germatranyl)tin(IV) propionate

(CH₃(CH₂)3)2Sn(O₂CCH₂CH(C₆H₅)Ge((OCH₂CH₂)3N))2(H₂O)