Triethanolamine

Base Information

• Chemical Name: Triethanolamine
• CAS No.: 102-71-6
• Deprecated CAS: 105655-27-4,126068-67-5,36549-53-8,36549-54-9,36549-55-0,36659-79-7,464917-26-8,1429745-86-7,126068-67-5,36549-54-9,36549-55-0,36659-79-7,464917-26-8
• Molecular Formula: C6H15NO3
• Molecular Weight: 149.19
• Hs Code.: 29321900
• European Community (EC) Number: 203-049-8
• ICSC Number: 1034
• NSC Number: 36718
• UNII: 9O3K93S3TK
• DSSTox Substance ID: DTXSID9021392
• Nikkaji Number: J805B
• Wikipedia: Triethanolamine
• Wikidata: Q424314
• NCI Thesaurus Code: C80948
• RXCUI: 38623
• Metabolomics Workbench ID: 45586
• ChEMBL ID: CHEMBL446061
• Mol file: 102-71-6.mol

Synonyms:2,2',2''-nitrilotriethanol;triethanolamine;triethanolamine acetate;triethanolamine citrate;triethanolamine citrate (1:1);triethanolamine copper salt;triethanolamine hydrochloride;triethanolamine iodohydrate;triethanolamine maleate;triethanolamine phosphate;triethanolamine sulfate;triethanolamine sulfate (2:1);triethanolamine sulfite (1:1);triethanolamine tartrate (1:1), (R-(R*,R*))-isomer;triethanolamine titanium salt;triethanolammonium chloride;trolamine

Chemical Property of Triethanolamine

Chemical Property:

• Appearance/Colour: Clear, amber viscous liquid
• Vapor Pressure: 0.01 mm Hg ( 20 °C)
• Melting Point: 21 °C
• Refractive Index: n20/D 1.485(lit.)
• Boiling Point: 335.4 °C at 760 mmHg
• PKA: 7.8(at 25℃)
• Flash Point: 185 °C
• PSA: 63.93000
• Density: 1.171 g/cm³
• LogP: -1.73470
• Storage Temp.: Store at RT.
• Sensitive.: Air Sensitive & Hygroscopic
• Solubility.: H2O: 1 M, clear, colorless
• Water Solubility.: soluble
• XLogP3: -1
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 6
• Exact Mass: 149.10519334
• Heavy Atom Count: 10
• Complexity: 55.7

Purity/Quality:

99% ^*data from raw suppliers

Triethanolamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38-36
• Safety Statements: 26-39-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Nitrogen Compounds -> Ethanolamines
• Canonical SMILES: C(CO)N(CCO)CCO
• Recent ClinicalTrials: Biafine Cream to Reduce Side Effects of Radiation Therapy in Patients Receiving Treatment for Advanced Head and Neck Cancer
• Inhalation Risk: Evaporation at 20 °C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed.
• Effects of Short Term Exposure: The substance is irritating to the eyes, skin and respiratory tract.
• Effects of Long Term Exposure: Repeated or prolonged contact may cause skin sensitization.
• Cement Additive: Triethanolamine (TEA) serves as a multi-functional additive in cement-based materials, acting as both a grinding aid during the cement comminution process and a regulator of setting time for cement hydrations. Its dual function as a grinding aid and setting time regulator provides efficiency and convenience in cement manufacturing processes.
• Surfactant and pH Adjuster in Cosmetic Products: Triethanolamine (TEA) is used as an ingredient in cosmetic products where it functions as a surfactant or pH adjuster. The Cosmetic Ingredient Review (CIR) Expert Panel has reviewed TEA and concluded that it is safe for use in cosmetic formulations designed for discontinuous, brief use followed by thorough rinsing. However, in products intended for prolonged contact with the skin, the concentration of TEA should not exceed 5%, and it should not be used in products containing N-nitrosating agents.
• Corrosion Inhibitor: TEA is utilized as a corrosion inhibitor in various products, including metalworking fluids, oils, fuels, paints, and inks. It helps to protect metal surfaces from corrosion and degradation.
• Intermediate in Various Products: TEA acts as an intermediate in the production of a wide range of products across different industries. It is used in the manufacturing process of cosmetics, personal care products, cement, herbicides, and algicides.
• Common Products: TEA is present in a variety of common household and industrial products, including sunscreen lotions, liquid laundry detergents, dishwashing liquids, general cleaners, hand sanitizers, polishes, metalworking fluids, paints, shaving cream, and printing inks. Its versatile properties make it valuable in enhancing the performance and functionality of these products.

Technology Process of Triethanolamine

There total 44 articles about Triethanolamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.1%

oxirane (75-21-8,99932-75-9) + ethanolamine (141-43-5) → triethanolamine (102-71-6,64114-46-1) + 2,2'-iminobis[ethanol] (111-42-2)

Guidance literature:

With ammonia; ZSM-5 type zeolite ion exchange with lanthanum; at 45 ℃; under 75007.5 Torr; Industry scale; Adiabatic conditions;

Reference yield: 52.1%

oxirane (75-21-8,99932-75-9) + ammonia (7664-41-7) → triethanolamine (102-71-6,64114-46-1) + ethanolamine (141-43-5) + 2,2'-iminobis[ethanol] (111-42-2)

Guidance literature:

water; at 48.84 - 76.84 ℃; for 0.25h; under 12751.3 Torr;

Reference yield:

→ propylene glycol (57-55-6,63625-56-9) + triethanolamine (102-71-6,64114-46-1)

Guidance literature:

upstream raw materials:

oxirane

ethanolamine

tris-(2-chloro-ethyl)-amine

tris(2-hydroxyethyl)amine-N-oxide

Downstream raw materials:

tris-[2-(4-nitro-benzoyloxy)-ethyl]-amine

Glycolaldehyde

2,2'-iminobis[ethanol]

tris-(2-acetoxy-ethyl)-amine

Refernces

• 1、 Xu,Smid. "AFFINITIES OF CROWN ETHERS, GLYMES, AND POLYAMINES FOR ALKALI PICRATES IN TOLUENE. APPLICATION OF POLYMER-SUPPORTED LINEAR POLYETHERS.". . p. 3790 - 3796. Retrieved 1984.
• 2、 Ohtani, Bunsho,Osaki, Haruyoshi,Nishimoto, Sei-ichi,Kagiya, Tsutomu. "A REDOX COMBINED PHOTOCATALYSIS: NEW METHOD OF N-ALKYLATION OF AMMONIA BY TiO2/Pt SUSPENDED IN ALCOHOLS". . p. 2019 - 2022. Retrieved 1986.
• 3、 Brown, Herbert C.,Rangaishenvi, Milind V.. "Organoboranes. LI. Convenient procedures for the recovery of pinanediol in asymmetric synthesis via one-carbon homologation of boronic esters". . p. 15 - 30. Retrieved 1988.
• 4、 Zhang, Xiaoting,Wang, Shujuan,Jiang, Zikang,Li, Yu,Jing, Xinli. "Boronic Ester Based Vitrimers with Enhanced Stability via Internal Boron-Nitrogen Coordination". supporting information. p. 21852 - 21860. Retrieved 2021/01/11.
• 5、 -. "AQUEOUS COMPOSITION AND METHOD OF PRODUCING CHLORINE DIOXIDE USING AQUEOUS COMPOSITION". . . Retrieved 2018/07/15.