C₂₈H₃₅F₃N₄O

Base Information

Chemical Name:C₂₈H₃₅F₃N₄O
CAS No.:1457967-32-6
Molecular Formula:C₂₈H₃₅F₃N₄O
Molecular Weight:500.607
Hs Code.:

C<sub>28</sub>H<sub>35</sub>F<sub>3</sub>N<sub>4</sub>O

Synonyms:

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Chemical Property of C₂₈H₃₅F₃N₄O

Chemical Property:

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Technology Process of C₂₈H₃₅F₃N₄O

There total 6 articles about C₂₈H₃₅F₃N₄O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1457967-22-4
N⁴-benzyl-3-nitro-6-(4-(trifluoromethoxy)benzyl)-N²-(2,4,4-trimethylpentan-2-yl)pyridine-2,4-diamine

: 1457967-32-6
C₂₈H₃₅F₃N₄O

Guidance literature:: With ammonium formate; zinc; In methanol; at 20 ℃; for 0.166667h;
DOI:10.1039/c3ob40816g

Reference yield:

: 2587-02-2
2,6-dichloro-[4]pyridylamine

: 1457967-32-6
C₂₈H₃₅F₃N₄O

Guidance literature:: Multi-step reaction with 6 steps

1.1: sulfuric acid; nitric acid / 1 h / 0 - 20 °C

2.1: sulfuric acid / 0.5 h / 90 °C

3.1: sodium hydride / tetrahydrofuran / 1 h / 0 °C / Inert atmosphere

3.2: 2 h / 20 °C

4.1: triethylamine / dichloromethane / 48 h / Reflux

5.1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; caesium carbonate / water; 1,4-dioxane / 18 h / 90 °C / Inert atmosphere; Sealed tube

6.1: zinc; ammonium formate / methanol / 0.17 h / 20 °C

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sulfuric acid; nitric acid; ammonium formate; sodium hydride; caesium carbonate; triethylamine; zinc; In tetrahydrofuran; 1,4-dioxane; methanol; dichloromethane; water; 5.1: |Suzuki Coupling;
DOI:10.1039/c3ob40816g

Reference yield:

: 2587-03-3
2,6-dichloro-N-nitro-4-pyridinamine

: 1457967-32-6
C₂₈H₃₅F₃N₄O

Guidance literature:: Multi-step reaction with 5 steps

1.1: sulfuric acid / 0.5 h / 90 °C

2.1: sodium hydride / tetrahydrofuran / 1 h / 0 °C / Inert atmosphere

2.2: 2 h / 20 °C

3.1: triethylamine / dichloromethane / 48 h / Reflux

4.1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; caesium carbonate / water; 1,4-dioxane / 18 h / 90 °C / Inert atmosphere; Sealed tube

5.1: zinc; ammonium formate / methanol / 0.17 h / 20 °C

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sulfuric acid; ammonium formate; sodium hydride; caesium carbonate; triethylamine; zinc; In tetrahydrofuran; 1,4-dioxane; methanol; dichloromethane; water; 4.1: |Suzuki Coupling;
DOI:10.1039/c3ob40816g