6-Methoxy-L-fucose

Base Information

• Chemical Name: 6-Methoxy-L-fucose
• CAS No.: 10287-49-7
• Molecular Formula: C₇H₁₄O₆
• Molecular Weight: 194.185
• Mol file: 10287-49-7.mol

Synonyms:

Chemical Property of 6-Methoxy-L-fucose

Chemical Property:

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6-Methoxy-L-fucose

There total 15 articles about 6-Methoxy-L-fucose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

C35H38O6 (1362023-07-1) → 6-O-methyl-D-mannopyranose (10287-49-7,14199-58-7,24436-14-4,31505-26-7,31505-27-8,31505-28-9,31505-29-0,87936-86-5,87936-87-6,27552-12-1)

Guidance literature:

With 20 % Pd(OH)2/C; hydrogen; acetic acid; In methanol; for 48h; under 60.006 Torr;

DOI:10.1039/c2cc17393j

Reference yield: 39.0%

methoxyacetaldehyde (10312-83-1) + Glycolaldehyde (141-46-8) → 6-O-Methyl-D-glucose (10287-49-7,14199-58-7,24436-14-4,27552-12-1,31505-26-7,31505-27-8,31505-28-9,31505-29-0,87936-86-5,87936-87-6)

Guidance literature:

With Escherichia coli D-fructose-6-phosphate aldolase A₁₂₉T/A₁₆₅G/S₁₆₆G mutant; for 24h; Time; stereoselective reaction; Enzymatic reaction;

DOI:10.1038/nchem.2321

Reference yield: 4.0%

methoxyacetaldehyde (10312-83-1) + Glycolaldehyde (141-46-8) → 6-O-Methyl-D-glucose (10287-49-7,14199-58-7,24436-14-4,27552-12-1,31505-26-7,31505-27-8,31505-28-9,31505-29-0,87936-86-5,87936-87-6) + C7H14O6

Guidance literature:

methoxyacetaldehyde; Glycolaldehyde; With Escherichia coli D-fructose-6-phosphate aldolase A₁₂₉T/A₁₆₅G mutant; Enzymatic reaction;

With Escherichia coli D-fructose-6-phosphate aldolase A₁₂₉T mutant; stereoselective reaction; Enzymatic reaction;

DOI:10.1038/nchem.2321

upstream raw materials:

Benzyl 2,3,4-tri-O-benzyl-α-D-galactopyranosid

O¹,O²;O³,O⁴-diisopropylidene-O⁶-methyl-α-D-galactopyranose

dihydroxyacetone phosphate

2-hydroxy-3-methoxypropionaldehyde

Downstream raw materials:

6-O-methylglucitol

2-O-acetyl-3,4-di-O-benzyl-6-O-methyl-α-D-galactopyranosyl bromide

3,4-di-O-benzyl-1,2-O-(1-methoxyethylidene)-6-O-methyl-α-D-galactopyranose

methyl 2-acetamido-3-O-(3,4-di-O-benzyl-6-O-methyl-β-D-galactopyranosyl)-6-O-benzyl-2-deoxy-β-D-glucopyranoside