Technology Process of (22E,24R)-7α-Hydroxy-5α-ergost-2,22-dien-6-one
There total 5 articles about (22E,24R)-7α-Hydroxy-5α-ergost-2,22-dien-6-one which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
toluene-4-sulfonic acid; lithium bromide;
In
N,N-dimethyl-formamide;
for 1.5h;
Heating;
DOI:10.1055/s-1989-27273
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 93 percent / Li, liq. NH3 / ethyl acetate / 0.08 h / -78 °C
2: 100 percent / Et3N / CH2Cl2 / 0.33 h / 0 °C
3: 82 percent / MCPBA / CH2Cl2 / 1 h / Ambient temperature
4: 83 percent / TsOH, LiBr / dimethylformamide / 1.5 h / Heating
With
ammonia; lithium; toluene-4-sulfonic acid; triethylamine; 3-chloro-benzenecarboperoxoic acid; lithium bromide;
In
dichloromethane; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1055/s-1989-27273
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 67 percent / chromic acid / pyridine / 5 h / Ambient temperature
2: 93 percent / Li, liq. NH3 / ethyl acetate / 0.08 h / -78 °C
3: 100 percent / Et3N / CH2Cl2 / 0.33 h / 0 °C
4: 82 percent / MCPBA / CH2Cl2 / 1 h / Ambient temperature
5: 83 percent / TsOH, LiBr / dimethylformamide / 1.5 h / Heating
With
ammonia; chromic acid; lithium; toluene-4-sulfonic acid; triethylamine; 3-chloro-benzenecarboperoxoic acid; lithium bromide;
In
pyridine; dichloromethane; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1055/s-1989-27273