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(22E,24R)-3α,5-cyclo-5α-ergosta-7,22-dien-6β-ol is a complex steroidal compound characterized by its unique molecular structure. It features a cycloalkane ring at the 3α,5 position and a double bond between carbons 22 and 23, with the 22E and 24R stereochemistry indicating the specific orientation of the double bond and the hydroxyl group at the 24 position. (22E,24R)-3α,5-cyclo-5α-ergosta-7,22-dien-6β-ol belongs to the family of ergostane steroids, which are derived from the parent compound ergostane. It is a 6β-hydroxylated derivative, meaning that a hydroxyl group is attached to the 6th carbon in the β-configuration. Such compounds are of interest in the field of organic chemistry and may have potential applications in pharmaceuticals or as intermediates in the synthesis of other biologically active molecules.

2774-59-6

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2774-59-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 2774-59-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,7,7 and 4 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 2774-59:
(6*2)+(5*7)+(4*7)+(3*4)+(2*5)+(1*9)=106
106 % 10 = 6
So 2774-59-6 is a valid CAS Registry Number.

2774-59-6Upstream product

2774-59-6Relevant academic research and scientific papers

Biological Activity of Brassinosteroids – Direct Comparison of Known and New Analogs in planta

Wendeborn, Sebastian,Lachia, Mathilde,Jung, Pierre M. J.,Leipner, J?rg,Brocklehurst, David,De Mesmaeker, Alain,Gaus, Katharina,Mondière, Régis

, (2017)

A systematic investigation of structural modifications of brassinosteroids is presented. We describe in detail their synthetic preparation, which includes significant improvements of previously reported protocols as well as access to new analogs with functional modifications of the steroid skeleton and of the C(17)-attached side chain. We report the biological potency of the prepared brassinosteroid analogs as plant hormones, which were carefully established in the French bean second internode elongation assay and discuss our observations in light of the recently reported structural data detailing the molecular interactions between brassinolide in the trimeric complex with the protein receptors kinases BRASSINOSTEROID INSENSITIVE 1 (BRI1) and SOMATIC EMBRYOGENESIS RECEPTOR KINASE 1 (SERK1). In a further part of this work we describe the preparation of H2O-soluble pro-forms of 24-epicastasterone and we discuss their physical properties, hydrolytic stabilities and biological activity.

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