Benzenesulfonic acid, 4-methyl-, 2-cyclohexylhydrazide

Base Information

• Chemical Name: Benzenesulfonic acid, 4-methyl-, 2-cyclohexylhydrazide
• CAS No.: 1146-49-2
• Molecular Formula: C13H20N2O2S
• Molecular Weight: 268.38
• Mol file: 1146-49-2.mol

Synonyms:

Chemical Property of Benzenesulfonic acid, 4-methyl-, 2-cyclohexylhydrazide

Chemical Property:

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzenesulfonic acid, 4-methyl-, 2-cyclohexylhydrazide

There total 5 articles about Benzenesulfonic acid, 4-methyl-, 2-cyclohexylhydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

N'-cyclohexylidene-4-methylbenzene-1-sulfonohydrazide (4545-18-0) → <2-(p-tolylsulfonyl)hydrazino>cyclohexane (1146-49-2)

Guidance literature:

With triethylsilane; trifluoroacetic acid; at 0 ℃; for 1h;

DOI:10.1055/s-1996-4196

Reference yield: 76.0%

2-Nitrocyclohexanone tosylhydrazone (85814-68-2) → <2-(p-tolylsulfonyl)hydrazino>cyclohexane (1146-49-2)

Guidance literature:

With sodium tetrahydroborate; In methanol; Ambient temperature;

Reference yield:

cyclohexanone (108-94-1,11119-77-0,9003-41-2,9075-99-4) → <2-(p-tolylsulfonyl)hydrazino>cyclohexane (1146-49-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 91 percent / hexane / 2 h / Ambient temperature

2: 89 percent / Et₃SiH, CF₃COOH / 1 h / 0 °C

With triethylsilane; trifluoroacetic acid; In hexane;

DOI:10.1055/s-1996-4196

upstream raw materials:

2-Nitrocyclohexanone tosylhydrazone

N'-cyclohexylidene-4-methylbenzene-1-sulfonohydrazide

cyclohexanone

toluene-4-sulfonic acid hydrazide

Downstream raw materials:

2-methoxycyclohexane

cyclohexyl ethyl ether

cyclohexyl iso-propyl ether

cyclohexylphenyl ether

Refernces

• 1、 Ballini, Roberto,Castagnani, Roberto,Marcantoni, Enrico. "A Novel, Chemoselective, "One-pot" Procedure for the Simultaneous Denitration-Deoxygenation of 2-Nitroketones by TsNHNH2-NaBH4". . p. 3161 - 3162. Retrieved 2007/10/02.