(2,2-DIMETHYL-3,4-DIHYDRO-2H-CHROMEN-6-YL)ACETIC ACID

Base Information

• Chemical Name: (2,2-DIMETHYL-3,4-DIHYDRO-2H-CHROMEN-6-YL)ACETIC ACID
• CAS No.: 109978-87-2
• Molecular Formula: C₁₃H₁₆O₃
• Molecular Weight: 220.268
• Mol file: 109978-87-2.mol

Synonyms:

Chemical Property of (2,2-DIMETHYL-3,4-DIHYDRO-2H-CHROMEN-6-YL)ACETIC ACID

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

(2,2-Dimethyl-3,4-dihydro-2H-chromen-6-yl)aceticAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2,2-DIMETHYL-3,4-DIHYDRO-2H-CHROMEN-6-YL)ACETIC ACID

There total 4 articles about (2,2-DIMETHYL-3,4-DIHYDRO-2H-CHROMEN-6-YL)ACETIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C14H16O5 → (2,2-dimethylchroman-6-yl)acetic acid (109978-87-2)

Guidance literature:

With copper(I) oxide; In acetonitrile; at 80 ℃; for 5h;

DOI:10.1055/s-2007-983803

Reference yield:

2,2-dimethyl-6-acetylchroman (32333-31-6) → (2,2-dimethylchroman-6-yl)acetic acid (109978-87-2)

Guidance literature:

With pyridine; ammonium hydroxide; sulfur; at 120 ℃; Erhitzen des Reaktionsprodukts mit wss. Natronlauge;

DOI:10.1039/jr9550004347

Reference yield:

4-Hydroxyacetophenone (99-93-4) → (2,2-dimethylchroman-6-yl)acetic acid (109978-87-2)

Guidance literature:

Multi-step reaction with 2 steps

1: iodine / 150 °C

2: sulfur; pyridine; aqueous ammonia / 120 °C / Erhitzen des Reaktionsprodukts mit wss. Natronlauge

With pyridine; ammonium hydroxide; iodine; sulfur;

DOI:10.1039/jr9550004347

upstream raw materials:

2,2-dimethyl-6-acetylchroman

4-Hydroxyacetophenone

isoprene