4H-Pyrimido(6,1-a)isoquinolin-4-one, 2,3,6,7-tetrahydro-9,10-dimethoxy-3-(1-methylethyl)-2-((2,4,6-trimethylphenyl)imino)-

Base Information

Chemical Name:4H-Pyrimido(6,1-a)isoquinolin-4-one, 2,3,6,7-tetrahydro-9,10-dimethoxy-3-(1-methylethyl)-2-((2,4,6-trimethylphenyl)imino)-
CAS No.:80023-89-8
Molecular Formula:C₂₆H₃₁N₃O₃
Molecular Weight:433.55
Hs Code.:
ChEMBL ID:CHEMBL34261

Synonyms:BRN 0867340;4H-Pyrimido(6,1-a)isoquinolin-4-one, 2,3,6,7-tetrahydro-9,10-dimethoxy-3-(1-methylethyl)-2-((2,4,6-trimethylphenyl)imino)-;80023-89-8;CHEMBL34261;SCHEMBL2457415;SCHEMBL2457416;ZVGPHEIZESYWTE-UHFFFAOYSA-N;LS-136230;9,10-dimethoxy-3-isopropyl-2-mesitylimino-2,3,6,7-tetrahydro-4H-pyrimido(6,1-a)isoquinolin-4-one;9,10-dimethoxy-3-isopropyl-2-mesitylimino-2,3,6,7-tetrahydro-4H-pyrimido(6,1-a)isoquinoline-4-one

Suppliers and Price of 4H-Pyrimido(6,1-a)isoquinolin-4-one, 2,3,6,7-tetrahydro-9,10-dimethoxy-3-(1-methylethyl)-2-((2,4,6-trimethylphenyl)imino)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4H-Pyrimido(6,1-a)isoquinolin-4-one, 2,3,6,7-tetrahydro-9,10-dimethoxy-3-(1-methylethyl)-2-((2,4,6-trimethylphenyl)imino)-

Chemical Property:

Vapor Pressure:1.26E-14mmHg at 25°C
Boiling Point:605.8°C at 760 mmHg
Flash Point:320.2°C
Density:1.18g/cm³
XLogP3:4.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:433.23654186
Heavy Atom Count:32
Complexity:751

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C(C(=C1)C)N=C2C=C3C4=CC(=C(C=C4CCN3C(=O)N2C(C)C)OC)OC)C

Technology Process of 4H-Pyrimido(6,1-a)isoquinolin-4-one, 2,3,6,7-tetrahydro-9,10-dimethoxy-3-(1-methylethyl)-2-((2,4,6-trimethylphenyl)imino)-

There total 7 articles about 4H-Pyrimido(6,1-a)isoquinolin-4-one, 2,3,6,7-tetrahydro-9,10-dimethoxy-3-(1-methylethyl)-2-((2,4,6-trimethylphenyl)imino)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 5.0%

: 75-30-9
2-iodo-propane

: 76536-66-8
9,10-dimethoxy-2-(2,4,6-trimethylanilino)-6,7-dihydro-4H-pyrimido(6,1-a)isoquinolin-4-one

: 83070-39-7
2-(N-isopropyl-2,4,6-trimethyl-anilino)-9,10-dimethoxy-6,7-dihydro-pyrimido[6,1-a]isoquinolin-4-one

: 80023-89-8
3-isopropyl-9,10-dimethoxy-2-(2,4,6-trimethyl-phenylimino)-2,3,6,7-tetrahydro-pyrimido[6,1-a]isoquinolin-4-one

Guidance literature:: With potassium carbonate; In acetone; Heating;
DOI:10.1021/jm00377a016

Reference yield:

: 25017-47-4
N-<2-(3,4-dimethoxyphenylethyl)>urea

: 80023-89-8
3-isopropyl-9,10-dimethoxy-2-(2,4,6-trimethyl-phenylimino)-2,3,6,7-tetrahydro-pyrimido[6,1-a]isoquinolin-4-one

Guidance literature:: Multi-step reaction with 4 steps

1: 75 percent / EtONa / ethanol / 16 h / Heating

2: 100 percent / POCl₃ / 2.5 h / 100 - 110 °C

3: 74 percent / CHCl₃ / 20 h / Heating

4: 5 percent / K₂CO₃ / acetone / Heating

With sodium ethanolate; potassium carbonate; trichlorophosphate; In ethanol; chloroform; acetone;
DOI:10.1021/jm00377a016

Reference yield:

: 91209-74-4
1-(carbamoylmethylene)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline

: 80023-89-8
3-isopropyl-9,10-dimethoxy-2-(2,4,6-trimethyl-phenylimino)-2,3,6,7-tetrahydro-pyrimido[6,1-a]isoquinolin-4-one

Guidance literature:: Multi-step reaction with 4 steps

1: 87 percent / EtONa / ethanol / 8 h / Heating

2: 87 percent / POCl₃ / 4 h / 110 °C

3: 74 percent / CHCl₃ / 20 h / Heating

4: 5 percent / K₂CO₃ / acetone / Heating

With sodium ethanolate; potassium carbonate; trichlorophosphate; In ethanol; chloroform; acetone;
DOI:10.1021/jm00377a016