N'-(N-benzoylglycinyl)isonicotinic hydrazide

Base Information

• Chemical Name: N'-(N-benzoylglycinyl)isonicotinic hydrazide
• CAS No.: 109408-34-6
• Molecular Formula: C₁₅H₁₄N₄O₃
• Molecular Weight: 298.301
• Mol file: 109408-34-6.mol

Synonyms:

Chemical Property of N'-(N-benzoylglycinyl)isonicotinic hydrazide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N'-(N-benzoylglycinyl)isonicotinic hydrazide

There total 4 articles about N'-(N-benzoylglycinyl)isonicotinic hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

isoniazid (54-85-3,7640-37-1) + 1-(N-benzoyl-glycyloxy)-1H-benzotriazole (62912-04-3) → N'-(N-benzoylglycinyl)isonicotinic hydrazide (109408-34-6)

Guidance literature:

In N,N-dimethyl-formamide; at 60 ℃; for 0.166667h; under 7500.75 Torr; Microwave irradiation;

DOI:10.5012/jkcs.2010.54.4.419

Reference yield:

isonicotinoyl chloride hydrochloride (39178-35-3) + (2-hydrazinyl-2-oxoethyl)benzamide (2443-68-7) → N'-(N-benzoylglycinyl)isonicotinic hydrazide (109408-34-6)

Guidance literature:

With pyridine;

DOI:10.1002/hlca.19560390127

Reference yield:

isoniazid (54-85-3,7640-37-1) + hippuroylmercapto-acetic acid (2979-64-8) → N'-(N-benzoylglycinyl)isonicotinic hydrazide (109408-34-6)

Guidance literature:

in gepufferter wss. Loesung bei pH 3 unter Zusatz von DMF;

upstream raw materials:

isoniazid

hippuroylmercapto-acetic acid

isonicotinoyl chloride hydrochloride

(2-hydrazinyl-2-oxoethyl)benzamide

Refernces