2443-68-7

Basic information

• Product Name: N-(2-HYDRAZINO-2-OXOETHYL)BENZAMIDE
• Synonyms: N-(2-HYDRAZINO-2-OXOETHYL)BENZAMIDE;AKOS BBS-00001046;IFLAB-BB F1386-0419
• CAS NO: 2443-68-7
• Molecular Formula: C₉H₁₁N₃O₂
• Molecular Weight: 193.2
• Mol File: 2443-68-7.mol
• Article Data: 13

Chemical Properties

• Melting Point: 130-132 °C(Solv: ethanol (64-17-5))
• Boiling Point: 537.8°C at 760 mmHg
• Flash Point: 279°C
• Appearance: /
• Density: 1.239g/cm³
• Vapor Pressure: 1.23E-11mmHg at 25°C
• Refractive Index: 1.577
• PKA: 12.43±0.37(Predicted)
• CAS DataBase Reference: N-(2-HYDRAZINO-2-OXOETHYL)BENZAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-HYDRAZINO-2-OXOETHYL)BENZAMIDE(2443-68-7)
• EPA Substance Registry System: N-(2-HYDRAZINO-2-OXOETHYL)BENZAMIDE(2443-68-7)

Safety Data

• Hazardous Substances Data: 2443-68-7(Hazardous Substances Data)

Usage

General Description

N-(2-HYDRAZINO-2-OXOETHYL)BENZAMIDE is a chemical compound with a molecular formula C9H10N4O2. It is a benzamide derivative with a hydrazine group attached to the ethyl carbonyl group. N-(2-HYDRAZINO-2-OXOETHYL)BENZAMIDE is commonly used in organic synthesis and pharmaceutical research due to its potential applications in the development of new drugs and medications. It is also known for its diverse biological activities, including antimicrobial, antifungal, and antitumor properties. N-(2-HYDRAZINO-2-OXOETHYL)BENZAMIDE is a versatile chemical that is widely studied for its potential therapeutic benefits and industrial applications in various fields.

InChI:InChI=1/C9H11N3O2/c10-12-8(13)6-11-9(14)7-4-2-1-3-5-7/h1-5H,6,10H2,(H,11,14)(H,12,13)

Upstream product

• 1499-53-2 ethyl hippurate 
• 64-17-5 ethanol 
• 7803-57-8 hydrazine hydrate 
• 65-85-0 benzoic acid 
• 98-88-4 benzoyl chloride 
• 1205-08-9 methyl hippurate 
• 1377733-34-0 C₁₀H₁₁NO₃*ClH 
• 495-69-2 Hippuric Acid 
• 100373-37-3 hippuroyloxy-acetic acid ethyl ester 
• 57461-31-1 hippuroyl azide 
• 5813-81-0 hippuramide 

Downstream Products

• 15366-22-0 N,N'-dihippuroyl-hydrazine 
• 83530-35-2 1-hippuroyl thiosemicarbazide 
• 109408-34-6 N'-(N-benzoylglycinyl)isonicotinic hydrazide 
• 110181-51-6 N-(5-amino-1H-[1,2,4]triazol-3-ylmethyl)-benzamide 
• 137204-94-5 hippuric acid benzylidenehydrazide 
• 57461-31-1 hippuroyl azide 
• 126716-71-0 2-acetyl-pyridine-(N-benzoyl)glycyl hydrazone 
• 94583-53-6 Z-Gly-NH-NH-CO-CH₂-NH₂ 
• 99032-25-4 Bz-Gly-NH-NH-D-(CO-CH(NH₂)-CH₂-C₆H₅) 
• 1353636-11-9 (E)-N-(2-(2-((1H-indol-3-yl)methylene)hydrazinyl)-2-oxoethyl)benzamide 
• 115653-14-0 C₉H₇N₃O₂S 

Relevant articles and documents

Synthesis of some hippuric acid substrate linked novel pyrazoles as antimicrobial agents

Escalating resistance of microorganisms to the currently accessible antimicrobial drugs has forced to synthesize some novel biologically active compounds as efficient alternates via economical substrates. Hence, hippuric acid was used as one of the starting materials to synthesize pyrazole derivatives. All the synthesized compounds were characterized by IR, NMR (1H & 13C) and mass spectral data. The antimicrobial potential of synthesized compounds has been explored against four bacterial and two fungal strains. Among the 12 compounds, 3 compounds 8j, 8k and 8l were found to exhibit prominent antimicrobial potential as compared with the standards ciprofloxacin and amphotericin-B.

Synthesis of Hydrazones from Amino Acids and their Antimicrobial and Cytotoxic Activities

Hydrazones 6a–6n were synthesized from different amino acids with various aldehydes under reflux in methanol/ethanol. The structures of synthesized compounds were ascertained by elemental analysis and spectroscopic techniques. A comparative study of the antimicrobial activity and cytotoxicity was carried out of the N-protected amino acids, their esters, hydrazides, and the respective hydrazones, providing good results in cytotoxicity studies.

4-Thiazolidinone derivatives: Synthesis, antimicrobial, anticancer evaluation and QSAR studies

A series of 4-thiazolidinone derivatives (1-18) was synthesized and tested in vitro for its antimicrobial and anticancer potential. Synthesized compounds were found to be 5 more potent antimicrobial agents than anticancer agents. Anticancer screening resu