2-Amino-1-(4-iodophenyl)-4-phenyl-1H-pyrrole-3-carbonitrile

Base Information

• Chemical Name: 2-Amino-1-(4-iodophenyl)-4-phenyl-1H-pyrrole-3-carbonitrile
• CAS No.: 115998-08-8
• Molecular Formula: C₁₇H₁₂IN₃
• Molecular Weight: 385.207
• DSSTox Substance ID: DTXSID50553556
• Nikkaji Number: J1.377.299A
• Wikidata: Q82434166

Synonyms:115998-08-8;2-Amino-1-(4-iodophenyl)-4-phenyl-1H-pyrrole-3-carbonitrile;DTXSID50553556

Chemical Property of 2-Amino-1-(4-iodophenyl)-4-phenyl-1H-pyrrole-3-carbonitrile

Chemical Property:

• XLogP3: 4.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 385.00759
• Heavy Atom Count: 21
• Complexity: 390

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2=CN(C(=C2C#N)N)C3=CC=C(C=C3)I

Technology Process of 2-Amino-1-(4-iodophenyl)-4-phenyl-1H-pyrrole-3-carbonitrile

There total 1 articles about 2-Amino-1-(4-iodophenyl)-4-phenyl-1H-pyrrole-3-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

2-bromo-1-phenylethylidenemalononitrile (4651-78-9) + p-aminoiodobenzene (540-37-4) → 2-Amino-1-(4-iodo-phenyl)-4-phenyl-1H-pyrrole-3-carbonitrile (115998-08-8)

Guidance literature:

In propan-1-ol; 60 to 65 deg C, 1 h; RT, 1 h;

Reference yield: 79.0%

carbon disulfide (75-15-0,12122-00-8) + 2-Amino-1-(4-iodo-phenyl)-4-phenyl-1H-pyrrole-3-carbonitrile (115998-08-8) → 5-(4-Methoxy-phenyl)-7-phenyl-1,7-dihydro-pyrrolo[2,3-d]pyrimidine-2,4-dithione (121405-43-4)

Guidance literature:

In pyridine; at 60 - 65 ℃;

Reference yield: 71.0%

2-Amino-1-(4-iodo-phenyl)-4-phenyl-1H-pyrrole-3-carbonitrile (115998-08-8) + orthoformic acid triethyl ester (122-51-0) → N-[3-cyano-1-(4-iodo-phenyl)-4-phenyl-1H-pyrrol-2-yl]-formimidic acid ethyl ester (311347-71-4)

Guidance literature:

Heating;

DOI:10.1002/jhet.5570370415

upstream raw materials:

2-bromo-1-phenylethylidenemalononitrile

p-aminoiodobenzene

Downstream raw materials:

5-(4-Methoxy-phenyl)-7-phenyl-1,7-dihydro-pyrrolo[2,3-d]pyrimidine-2,4-dithione

7-(4-iodo-phenyl)-5-phenyl-3,7-dihydro-pyrrolo[2,3-d]pyrimidin-4-one

N-[3-cyano-1-(4-iodo-phenyl)-4-phenyl-1H-pyrrol-2-yl]-formimidic acid ethyl ester

4-chloro-7-(4-iodo-phenyl)-5-phenyl-7H-pyrrolo[2,3-d]pyrimidine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 115998-08-8 1H-Pyrrole-3-carbonitrile, 2-amino-1-(4-iodophenyl)-4-phenyl-

Send

Send

Metric Ton KG G Pound L ML

Send

Send