N-[4-(1-Piperazinyl)phenyl]acetamide

Base Information

Chemical Name:N-[4-(1-Piperazinyl)phenyl]acetamide
CAS No.:116290-77-8
Molecular Formula:C12H17N3O
Molecular Weight:219.286
Hs Code.:
UNII:LDV3HH98BM
Mol file:116290-77-8.mol

Synonyms:N-[4-(1-Piperazinyl)phenyl]acetamide;N-[4-(piperazin-1-yl)phenyl]acetamide;116290-77-8;LDV3HH98BM;SCHEMBL532005;YSAGBPKXODMPLA-UHFFFAOYSA-N;N-[4-(Piperazinyl)phenyl]acetamide;1-[4-(Acetylamino)phenyl]piperazine;Acetamide, N-[4-(1-piperazinyl)phenyl]-;EN300-1841973

Suppliers and Price of N-[4-(1-Piperazinyl)phenyl]acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-[4-(1-Piperazinyl)phenyl]acetamide

Chemical Property:

XLogP3:0.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:219.137162174
Heavy Atom Count:16
Complexity:230

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(=O)NC1=CC=C(C=C1)N2CCNCC2

Technology Process of N-[4-(1-Piperazinyl)phenyl]acetamide

There total 2 articles about N-[4-(1-Piperazinyl)phenyl]acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 116290-77-8
N-(4-piperazin-1-ylphenyl)-acetamide

Guidance literature:

Reference yield:

: 103-88-8
4-bromoacetanilide

: 116290-77-8
N-(4-piperazin-1-ylphenyl)-acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; DavePhos; lithium hexamethyldisilazane / tetrahydrofuran / 24 h / 65 °C / Schlenk technique; Inert atmosphere

2: palladium 10% on activated carbon; hydrogen / methanol / 4 h / 70 °C / 7500.75 Torr

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; palladium 10% on activated carbon; hydrogen; lithium hexamethyldisilazane; DavePhos; In tetrahydrofuran; methanol;
DOI:10.1002/ejoc.201403054