(4R)-Ethyl 4-methyl-2-oxocyclohexanecarboxylate

Base Information

Chemical Name:(4R)-Ethyl 4-methyl-2-oxocyclohexanecarboxylate
CAS No.:13368-67-7
Molecular Formula:C₁₀H₁₆O₃
Molecular Weight:184.235
Hs Code.:
DSSTox Substance ID:DTXSID801241299
Nikkaji Number:J1.028.542I

Synonyms:13368-67-7;(4R)-Ethyl 4-methyl-2-oxocyclohexanecarboxylate;DTXSID801241299;(4R)-Ethyl4-methyl-2-oxocyclohexanecarboxylate;Ethyl (4R)-4-methyl-2-oxocyclohexanecarboxylate;(4R)-2-Oxo-4alpha-methylcyclohexanecarboxylic acid ethyl ester

Suppliers and Price of (4R)-Ethyl 4-methyl-2-oxocyclohexanecarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of (4R)-Ethyl 4-methyl-2-oxocyclohexanecarboxylate

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:184.109944368
Heavy Atom Count:13
Complexity:210

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC(=O)C1CCC(CC1=O)C
Isomeric SMILES:CCOC(=O)C1CC[C@H](CC1=O)C

Technology Process of (4R)-Ethyl 4-methyl-2-oxocyclohexanecarboxylate

There total 5 articles about (4R)-Ethyl 4-methyl-2-oxocyclohexanecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 89-82-7,90449-51-7
pulegone

: 13368-67-7
(1Ξ,4R)-2-oxo-4-methyl-cyclohexanecarboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: water / 250 °C

2: ethanolic sodium ethylate / Erhitzen des Reaktionsprodukts in Gegenwart von Glaspulver und Eisenpulver bei vermindertem Druck

With water; sodium ethanolate;
DOI:10.1021/ja01261a024

Reference yield:

: 13368-65-5
(3R)-3-methylcyclohexanone

: 95-92-1
oxalic acid diethyl ester

: 13368-67-7
(1Ξ,4R)-2-oxo-4-methyl-cyclohexanecarboxylic acid ethyl ester

Guidance literature:: With sodium ethanolate; Erhitzen des Reaktionsprodukts in Gegenwart von Glaspulver und Eisenpulver bei vermindertem Druck;
DOI:10.1021/ja01261a024

Reference yield:

: 13368-65-5
(3R)-3-methylcyclohexanone

: 623-49-4
ethyl cyanoformate

: 13368-67-7
(1Ξ,4R)-2-oxo-4-methyl-cyclohexanecarboxylic acid ethyl ester

Guidance literature:: With lithium hexamethyldisilazane; In tetrahydrofuran; at -78 - 20 ℃; for 2h; regioselective reaction;
DOI:10.1016/j.tetlet.2011.12.015