C₂₈H₃₃N₃O₅S

Base Information

Chemical Name:C₂₈H₃₃N₃O₅S
CAS No.:1384352-78-6
Molecular Formula:C₂₈H₃₃N₃O₅S
Molecular Weight:523.653
Hs Code.:

C<sub>28</sub>H<sub>33</sub>N<sub>3</sub>O<sub>5</sub>S

Synonyms:

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Chemical Property of C₂₈H₃₃N₃O₅S

Chemical Property:

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Technology Process of C₂₈H₃₃N₃O₅S

There total 5 articles about C₂₈H₃₃N₃O₅S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 494799-19-8
methyl 2-bromo-3-cyclohexyl-1H-indole-6-carboxylate

: 1384352-78-6
C₂₈H₃₃N₃O₅S

Guidance literature:: Multi-step reaction with 6 steps

1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; lithium chloride / ethanol; toluene / 3.5 h / 80 °C

2: sodium hydride / N,N-dimethyl-formamide / 0 °C

3: water; lithium hydroxide / tetrahydrofuran; methanol / 15 h / 0 °C

4: HATU / N,N-dimethyl-formamide / 6 h / 20 °C

5: water; sodium hydroxide / tetrahydrofuran; methanol / 24 h / 20 °C

6: N-ethyl-N,N-diisopropylamine; HATU / N,N-dimethyl-formamide

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; water; sodium hydride; sodium carbonate; N-ethyl-N,N-diisopropylamine; HATU; lithium chloride; sodium hydroxide; lithium hydroxide; In tetrahydrofuran; methanol; ethanol; N,N-dimethyl-formamide; toluene; 1: Suzuki-Miyaura reaction;
DOI:10.1016/j.bmcl.2012.03.097

Reference yield:

: 494799-84-7
[3-cyclohexyl-2-(3-furyl)-6-(methoxycarbonyl)-1H-indol-1-yl]acetic acid

: 1384352-78-6
C₂₈H₃₃N₃O₅S

Guidance literature:: Multi-step reaction with 3 steps

1: HATU / N,N-dimethyl-formamide / 6 h / 20 °C

2: water; sodium hydroxide / tetrahydrofuran; methanol / 24 h / 20 °C

3: N-ethyl-N,N-diisopropylamine; HATU / N,N-dimethyl-formamide

With water; N-ethyl-N,N-diisopropylamine; HATU; sodium hydroxide; In tetrahydrofuran; methanol; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2012.03.097

Reference yield:

: 1384352-71-9
C₂₆H₃₀N₂O₄

: 1384352-78-6
C₂₈H₃₃N₃O₅S

Guidance literature:: Multi-step reaction with 2 steps

1: water; sodium hydroxide / tetrahydrofuran; methanol / 24 h / 20 °C

2: N-ethyl-N,N-diisopropylamine; HATU / N,N-dimethyl-formamide

With water; N-ethyl-N,N-diisopropylamine; HATU; sodium hydroxide; In tetrahydrofuran; methanol; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2012.03.097