494799-19-8Relevant articles and documents
HEPATITIS B CORE PROTEIN MODULATORS
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, (2018/04/13)
The present disclosure provides, in part, compounds having allosteric effector properties against Hepatitis B virus Cp. Also provided herein are methods of treating viral infections, such as hepatitis B, comprising administering to a patient in need thereof a disclosed compound of formula:
An efficient process for the large-scale synthesis of a 2,3,6-trisubstituted indole
Alorati, Anthony D.,Gibb, Andrew D.,Mullens, Peter R.,Stewart, Gavin W.
, p. 1947 - 1952 (2013/03/14)
The efficient synthesis of a key trisubstituted indole intermediate 1 is described. The synthetic route required the use of an aryl Grignard reagent which was not commercially available, and the large-scale formation of this fragment and the thermal evalu
CYCLOPROPYL FUSED INDOLOBENZAZEPINE HCV NS5B INHIBITORS
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Page/Page column 40-41, (2009/06/27)
The invention encompasses compounds of formula (I) as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV