((1-(p-Fluorobenzyl)-2-methyl-4-nitro-1H-imidazol-5-yl)thio)acetonitri le

Base Information

Chemical Name:((1-(p-Fluorobenzyl)-2-methyl-4-nitro-1H-imidazol-5-yl)thio)acetonitri le
CAS No.:77952-80-8
Molecular Formula:C₁₃H₁₁FN₄O₂S
Molecular Weight:306.32
Hs Code.:2933290090
Mol file:77952-80-8.mol

Synonyms:Acetonitrile,[[1-[(4-fluorophenyl)methyl]-2-methyl-4-nitro-1H-imidazol-5-yl]thio]- (9CI)

Suppliers and Price of ((1-(p-Fluorobenzyl)-2-methyl-4-nitro-1H-imidazol-5-yl)thio)acetonitri le

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
((1-(P-FLUOROBENZYL)-2-METHYL-4-NITRO-1H-IMIDAZOL-5-YL)THIO)ACETONITRI LE 95.00%
5MG
$ 499.83

Total 3 raw suppliers

Chemical Property of ((1-(p-Fluorobenzyl)-2-methyl-4-nitro-1H-imidazol-5-yl)thio)acetonitri le

Chemical Property:

Vapor Pressure:3.03E-10mmHg at 25°C
Boiling Point:503°C at 760 mmHg
Flash Point:258°C
PSA：112.73000
Density:1.39g/cm³
LogP:3.42598

Purity/Quality:

99% ^*data from raw suppliers

((1-(P-FLUOROBENZYL)-2-METHYL-4-NITRO-1H-IMIDAZOL-5-YL)THIO)ACETONITRI LE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of ((1-(p-Fluorobenzyl)-2-methyl-4-nitro-1H-imidazol-5-yl)thio)acetonitri le

There total 2 articles about ((1-(p-Fluorobenzyl)-2-methyl-4-nitro-1H-imidazol-5-yl)thio)acetonitri le which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 107-14-2
chloroacetonitrile

: 77952-62-6
3-(4-Fluoro-benzyl)-2-methyl-5-nitro-3H-imidazole-4-thiol; compound with ammonia

: 77952-80-8
[3-(4-Fluoro-benzyl)-2-methyl-5-nitro-3H-imidazol-4-ylsulfanyl]-acetonitrile

Guidance literature:: In methanol; water; Heating; 1.) reflux, 6-7 h, 2.) overnight;
DOI:10.1007/BF01149151

Reference yield:

: 68019-72-7
5-bromo-1-(4-fluoro-benzyl)-2-methyl-4-nitro-1H-imidazole

: 77952-80-8
[3-(4-Fluoro-benzyl)-2-methyl-5-nitro-3H-imidazol-4-ylsulfanyl]-acetonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: 69 percent / H₂S, ethanolic NH₃ / dimethylformamide / 0.17 h

2: 73 percent / methanol; H₂O / Heating; 1.) reflux, 6-7 h, 2.) overnight

With hydrogen sulfide; ammonia; In methanol; water; N,N-dimethyl-formamide;
DOI:10.1007/BF01149151