(6R-trans)-3-<<<<1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1H-pyrrol-1-yl)quinolin-3-yl>carbonyl>oxy>methyl>-8-oxo-7-<(phenoxyacetyl)amino>-5-thia-1-azabicyclo<4.2.0>oct-2-ene-2-carboxylic acid sodium salt

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Chemical Name:(6R-trans)-3-<<<<1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1H-pyrrol-1-yl)quinolin-3-yl>carbonyl>oxy>methyl>-8-oxo-7-<(phenoxyacetyl)amino>-5-thia-1-azabicyclo<4.2.0>oct-2-ene-2-carboxylic acid sodium salt
CAS No.:122949-53-5
Molecular Formula:C₃₂H₂₆FN₄O₈S*Na
Molecular Weight:668.635
Hs Code.:

(6R-trans)-3-<<<<1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1H-pyrrol-1-yl)quinolin-3-yl>carbonyl>oxy>methyl>-8-oxo-7-<(phenoxyacetyl)amino>-5-thia-1-azabicyclo<4.2.0>oct-2-ene-2-carboxylic acid sodium salt

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Chemical Property of (6R-trans)-3-<<<<1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1H-pyrrol-1-yl)quinolin-3-yl>carbonyl>oxy>methyl>-8-oxo-7-<(phenoxyacetyl)amino>-5-thia-1-azabicyclo<4.2.0>oct-2-ene-2-carboxylic acid sodium salt

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Technology Process of (6R-trans)-3-<<<<1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1H-pyrrol-1-yl)quinolin-3-yl>carbonyl>oxy>methyl>-8-oxo-7-<(phenoxyacetyl)amino>-5-thia-1-azabicyclo<4.2.0>oct-2-ene-2-carboxylic acid sodium salt

There total 1 articles about (6R-trans)-3-<<<<1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1H-pyrrol-1-yl)quinolin-3-yl>carbonyl>oxy>methyl>-8-oxo-7-<(phenoxyacetyl)amino>-5-thia-1-azabicyclo<4.2.0>oct-2-ene-2-carboxylic acid sodium salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 115622-74-7
(6R-trans)-3-(iodomethyl)-8-oxo-7-<(phenoxyacetyl)amino>-5-thia-1-azabicyclo<4.2.0>oct-2-ene-2-carboxylic acid allyl ester

: 122949-53-5
(6R-trans)-3-<<<<1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1H-pyrrol-1-yl)quinolin-3-yl>carbonyl>oxy>methyl>-8-oxo-7-<(phenoxyacetyl)amino>-5-thia-1-azabicyclo<4.2.0>oct-2-ene-2-carboxylic acid sodium salt

Guidance literature:: Multi-step reaction with 2 steps

1: 47 percent / dimethylformamide / 6 h

2: triethyl phosphite, palladium(II) acetate, sodium 2-ethylhexanoate / ethyl acetate; CH₂Cl₂ / 0.5 h

With palladium diacetate; triethyl phosphite; sodium 2-ethylhexanoic acid; In dichloromethane; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1021/jm00163a013