115622-74-7

Upstream product

• 701-99-5 Phenoxyacetyl chloride 

Downstream Products

• 122949-37-5 1-Ethyl-6-fluoro-4-oxo-7-pyrrol-1-yl-1,4-dihydro-quinoline-3-carboxylic acid (6R,7R)-2-allyloxycarbonyl-8-oxo-7-(2-phenoxy-acetylamino)-5-thia-1-aza-bicyclo[4.2.0]oct-2-en-3-ylmethyl ester 
• 115622-77-0 1-Ethyl-6-fluoro-4-oxo-7-thiomorpholin-4-yl-1,4-dihydro-quinoline-3-carboxylic acid (6R,7R)-2-allyloxycarbonyl-8-oxo-7-(2-phenoxy-acetylamino)-5-thia-1-aza-bicyclo[4.2.0]oct-2-en-3-ylmethyl ester 
• 122949-53-5 (6R-trans)-3-<<<<1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1H-pyrrol-1-yl)quinolin-3-yl>carbonyl>oxy>methyl>-8-oxo-7-<(phenoxyacetyl)amino>-5-thia-1-azabicyclo<4.2.0>oct-2-ene-2-carboxylic acid sodium salt 
• 115699-55-3 (6R-trans)-3-<<<<1-ethyl-6-fluoro-1,4-dihydro-7-(4-thiomorpholinyl)-4-oxoquinolin-3-yl>carbonyl>oxy>methyl>-8-oxo-7-<(phenoxyacetyl)amino>-5-thia-1-azabicyclo<4.2.0>oct-2-ene-2-carboxylic acid sodium salt 
• 115699-51-9 (6R-trans)-3-<<<<5-(4-fluorophenyl)-5,8-dihydro-8-oxo-1,3-dioxolo<4,5-g>quinolin-7-yl>carbonyl>oxy>methyl>-8-oxo-7-<(phenoxyacetyl)amino>-5-thia-1-azabicyclo<4.2.0>oct-2-ene-2-carboxylic acid sodium salt 
• 115699-51-9 [6R-(6α,7β)]-3-[[[[5-(4-fluorophenyl)-5,8-dihydro-8-oxo-1,3-dioxolo[4,5-g]quinolin-7-yl]carbonyl]oxy]methyl]-8-oxo-7-[(phenoxyacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sodium salt 

Relevant academic research and scientific papers

Optically-Detectable Enzyme Substrates and Their Method of Use

The present invention relates to compounds that are substrates for an enzyme, and upon reaction with the enzyme provide a detectable response, such as an optically detectable response. In particular, the compounds have utility in detecting the presence of a β-lactamase in a sample. In addition to the compounds, methods are disclosed for analyzing a sample for the presence of a β-lactmase, for example, as an indicator of expression of a nucleic acid sequence including a sequence coding for a β-lactmase. Kits are disclosed that include the disclosed compounds and additional components, for example, cells, antibodies, a β-lactmase or instructions for using the components in an assay.