Technology Process of Silane,
(1,1-dimethylethyl)[(2-methoxy-5-methyl-2,4-cyclohexadien-1-yl)methoxy
]diphenyl-
There total 1 articles about Silane,
(1,1-dimethylethyl)[(2-methoxy-5-methyl-2,4-cyclohexadien-1-yl)methoxy
]diphenyl- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 8 steps
1: 88 percent / pyridinium-p-toluenesulphonate / benzene / 16 h / Heating; Dean-Stark conditions
2: 71 percent / osmium tetroxide, N-methylmorpholine-N-oxide monohydrate / 2-methyl-propan-2-ol; tetrahydrofuran; H2O / 2 h / Ambient temperature
3: 43 percent / 1.) triethylamine; 2.) 4-dimethylaminopyridine / CH2Cl2 / 3 h / 0 °C / 1.) 10 min
4: 88 percent / potassium carbonate / methanol / 1 h / Ambient temperature
5: 100 percent / pyridinium-p-toluenesulphonate / CH2Cl2 / 0.33 h / Ambient temperature
6: 94 percent / acetic anhydride / 1 h / Heating
7: 1.) BH3*DMS; 2.) aq. NaOH, H2O2 / 1.) THF, 10 deg C, --> room temp., 16 h; 2.) H2O, 0 deg C, 1 h
8: 98 percent / palladium(II) chloride-acetonitrile complex / acetone / 7 h / Ambient temperature
With
dmap; dichloro bis(acetonitrile) palladium(II); sodium hydroxide; osmium(VIII) oxide; dimethylsulfide borane complex; dihydrogen peroxide; pyridinium p-toluenesulfonate; potassium carbonate; 4-methylmorpholine N-oxide; triethylamine;
In
tetrahydrofuran; methanol; dichloromethane; water; acetic anhydride; acetone; tert-butyl alcohol; benzene;
DOI:10.1016/S0040-4020(01)89182-1