Technology Process of (+/-)-trans-2-phenylcyclohexyl 3-acetamidobutanoate
There total 3 articles about (+/-)-trans-2-phenylcyclohexyl 3-acetamidobutanoate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 95 percent / triethylamine / acetone / 3 h / Heating
2: NH3 (gas) / methanol / 48 h / Ambient temperature
3: pyridine / tetrahydrofuran / 6 h / Heating
4: 94 percent / H2, AcOH, Ac2O / PtO2 / ethyl acetate / 3 h / 2250.2 - 3750.3 Torr
With
pyridine; ammonia; hydrogen; acetic anhydride; acetic acid; triethylamine;
platinum(IV) oxide;
In
tetrahydrofuran; methanol; ethyl acetate; acetone;
DOI:10.1021/ja00165a036
- Guidance literature:
-
Multi-step reaction with 2 steps
1: pyridine / tetrahydrofuran / 6 h / Heating
2: 94 percent / H2, AcOH, Ac2O / PtO2 / ethyl acetate / 3 h / 2250.2 - 3750.3 Torr
With
pyridine; hydrogen; acetic anhydride; acetic acid;
platinum(IV) oxide;
In
tetrahydrofuran; ethyl acetate;
DOI:10.1021/ja00165a036
- Guidance literature:
-
Multi-step reaction with 3 steps
1: NH3 (gas) / methanol / 48 h / Ambient temperature
2: pyridine / tetrahydrofuran / 6 h / Heating
3: 94 percent / H2, AcOH, Ac2O / PtO2 / ethyl acetate / 3 h / 2250.2 - 3750.3 Torr
With
pyridine; ammonia; hydrogen; acetic anhydride; acetic acid;
platinum(IV) oxide;
In
tetrahydrofuran; methanol; ethyl acetate;
DOI:10.1021/ja00165a036
