(+/-)-CR 1174

Base Information

• Chemical Name: (+/-)-CR 1174
• CAS No.: 97965-17-8
• Molecular Formula: C₂₀H₃₀N₂O₄
• Molecular Weight: 362.469
• Mol file: 97965-17-8.mol

Synonyms:

Chemical Property of (+/-)-CR 1174

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (+/-)-CR 1174

There total 7 articles about (+/-)-CR 1174 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 44.0%

di-n-propylamine (142-84-7) + 3,4-dimethyl-N-benzoyl-DL-glutamic anhydride (102743-18-0) → (+/-)-CR 1174 (97965-17-8) + 2-(3,4-Dimethyl-benzoylamino)-4-dipropylcarbamoyl-butyric acid (102743-00-0)

Guidance literature:

In water; at 5 - 10 ℃; for 3h;

Reference yield:

3,4-dimethylbenzoyl chloride (21900-23-2) → (+/-)-CR 1174 (97965-17-8)

Guidance literature:

Multi-step reaction with 3 steps

1: 85 percent / 1N NaOH / H₂O / 4 h / 15 - 20 °C

2: 82.5 percent / acetic anhydride / diisopropyl ether / 2 h / 70 °C

3: tetrahydrofuran / 3 h / 25 °C

With sodium hydroxide; acetic anhydride; In tetrahydrofuran; di-isopropyl ether; water;

Reference yield:

DL-4-(3,4-dimethyl-benzoyl-amino)-5-(di-n-propylamino)-5-oxo-pentanoic acid methyl ester → (+/-)-CR 1174 (97965-17-8)

Guidance literature:

With sodium hydroxide; In tetrahydrofuran; water; for 3h; Ambient temperature;

upstream raw materials:

di-n-propylamine

3,4-dimethyl-N-benzoyl-DL-glutamic anhydride

DL-glutamic acid-γ-methyl ester hydrochloride

3,4-dimethyl-N-benzoyl-DL-glutamic acid