Butanamide, N-phenyl-N-[1-(2-phenylethyl)-4-piperidinyl]-

Base Information Edit

Chemical Name:Butanamide, N-phenyl-N-[1-(2-phenylethyl)-4-piperidinyl]-
CAS No.:1169-70-6
Molecular Formula:C23H30N2O
Molecular Weight:350.504
Hs Code.:
UNII:07V1H7R6ZN
DSSTox Substance ID:DTXSID30347410
Nikkaji Number:J1.129.866D
Wikipedia:Butyrfentanyl
Wikidata:Q15408419
Metabolomics Workbench ID:152209
ChEMBL ID:CHEMBL4759342
Mol file:1169-70-6.mol

Butanamide, N-phenyl-N-[1-(2-phenylethyl)-4-piperidinyl]-

Synonyms:butyr-fentanyl;butyrfentanyl;butyryl-fentanyl;N-(1-phenylethyl)-4-piperidinyl)-N-phenylbutyramide

This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.

Chemical Property of Butanamide, N-phenyl-N-[1-(2-phenylethyl)-4-piperidinyl]- Edit

Chemical Property:

XLogP3:4.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:7
Exact Mass:350.235813585
Heavy Atom Count:26
Complexity:404

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCC(=O)N(C1CCN(CC1)CCC2=CC=CC=C2)C3=CC=CC=C3
Use Description Butanamide, N-phenyl-N-[1-(2-phenylethyl)-4-piperidinyl]-, is a chemical compound with applications in various fields. In the pharmaceutical industry, it plays a significant role as an active ingredient in certain medications, particularly in the treatment of pain and opioid dependence. This compound acts as a mu-opioid receptor antagonist and kappa-opioid receptor agonist, making it valuable for managing opioid addiction and as an analgesic in pain relief. In the field of medical research, it aids in the development of novel drugs for pain management and substance abuse treatment. Additionally, in the study of pharmacology, it serves as a tool for investigating opioid receptors and their interactions with potential therapeutic compounds. Its multifaceted utility underscores its significance in advancing pain management, addiction treatment, and scientific research, where it plays a pivotal role in drug development, healthcare, and understanding opioid pharmacology.

Technology Process of Butanamide, N-phenyl-N-[1-(2-phenylethyl)-4-piperidinyl]-

There total 7 articles about Butanamide, N-phenyl-N-[1-(2-phenylethyl)-4-piperidinyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 39742-60-4
1-(2-phenylethyl)-4-piperidinone

: 1169-70-6
N-<1-(2-Phenylethyl)-4-piperidyl>-N-phenylbutyramide

Guidance literature:: Multi-step reaction with 2 steps

1: 1) p-toluenesulfonic acid monohydrate, 2) NaBH₄ / 1) toluene, 22 h, reflux, 2) ethanol, rt, 3 h

2: toluene / 3 h / Heating

With sodium tetrahydroborate; toluene-4-sulfonic acid; In toluene;
DOI:10.1002/jhet.5570260329

Reference yield:

: 62-53-3
aniline

: 1169-70-6
N-<1-(2-Phenylethyl)-4-piperidyl>-N-phenylbutyramide

Guidance literature:: Multi-step reaction with 2 steps

1: 1) p-toluenesulfonic acid monohydrate, 2) NaBH₄ / 1) toluene, 22 h, reflux, 2) ethanol, rt, 3 h

2: toluene / 3 h / Heating

With sodium tetrahydroborate; toluene-4-sulfonic acid; In toluene;
DOI:10.1002/jhet.5570260329