2-(2,3-Dihydro-1,4-benzodioxin-2-yl)-5-(4-methoxyphenyl)-1,3,4-oxadiazole

Base Information

Chemical Name:2-(2,3-Dihydro-1,4-benzodioxin-2-yl)-5-(4-methoxyphenyl)-1,3,4-oxadiazole
CAS No.:951894-85-2
Molecular Formula:C₁₇H₁₄N₂O₄
Molecular Weight:310.309
Hs Code.:
DSSTox Substance ID:DTXSID001146584

Synonyms:2-(2,3-dihydro-1,4-benzodioxin-2-yl)-5-(4-methoxyphenyl)-1,3,4-oxadiazole;951894-85-2;DTXSID001146584;STL120006;AKOS002327459;AKOS016327135;MCULE-8016137368;2-(2,3-dihydro-1,4-benzodioxin-3-yl)-5-(4-methoxyphenyl)-1,3,4-oxadiazole

Suppliers and Price of 2-(2,3-Dihydro-1,4-benzodioxin-2-yl)-5-(4-methoxyphenyl)-1,3,4-oxadiazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(2,3-Dihydro-1,4-benzodioxin-2-yl)-5-(4-methoxyphenyl)-1,3,4-oxadiazole

Chemical Property:

XLogP3:2.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:310.09535693
Heavy Atom Count:23
Complexity:389

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C2=NN=C(O2)C3COC4=CC=CC=C4O3

Technology Process of 2-(2,3-Dihydro-1,4-benzodioxin-2-yl)-5-(4-methoxyphenyl)-1,3,4-oxadiazole

There total 3 articles about 2-(2,3-Dihydro-1,4-benzodioxin-2-yl)-5-(4-methoxyphenyl)-1,3,4-oxadiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 90557-92-9
2,3-dihydro-1,4-benzodioxane-2-carbohydrazide

: 100-09-4
4-methoxybenzoic acid

: 951894-85-2
2-(4-methoxy-phenyl)-5-(2,3-dihydro-1,4-benzodioxane-2-yl)-1,3,4-oxadiazole

Guidance literature:: With trichlorophosphate; Reflux;
DOI:10.3109/14756366.2010.489899

Reference yield:

: 4739-94-0
ethyl 2,3-dihydro-1,4-benzodioxin-2-carboxylate

: 951894-85-2
2-(4-methoxy-phenyl)-5-(2,3-dihydro-1,4-benzodioxane-2-yl)-1,3,4-oxadiazole

Guidance literature:: Multi-step reaction with 2 steps

1: hydrazine hydrate / ethanol / Reflux

2: trichlorophosphate / Reflux

With hydrazine hydrate; trichlorophosphate; In ethanol;
DOI:10.3109/14756366.2010.489899

Reference yield:

: 120-80-9,19481-10-8,37349-32-9
benzene-1,2-diol

: 951894-85-2
2-(4-methoxy-phenyl)-5-(2,3-dihydro-1,4-benzodioxane-2-yl)-1,3,4-oxadiazole

Guidance literature:: Multi-step reaction with 3 steps

1: potassium carbonate / acetone / 15 h / Reflux

2: hydrazine hydrate / ethanol / Reflux

3: trichlorophosphate / Reflux

With potassium carbonate; hydrazine hydrate; trichlorophosphate; In ethanol; acetone;
DOI:10.3109/14756366.2010.489899