C₂₆H₂₃N₃O₆S

Base Information

• Chemical Name: C₂₆H₂₃N₃O₆S
• CAS No.: 1354828-15-1
• Molecular Formula: C₂₆H₂₃N₃O₆S
• Molecular Weight: 505.551
• Mol file: 1354828-15-1.mol

Synonyms:

Chemical Property of C₂₆H₂₃N₃O₆S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₆H₂₃N₃O₆S

There total 11 articles about C₂₆H₂₃N₃O₆S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C19H21N3O6S (1080641-18-4) → C26H23N3O6S (1354828-15-1)

Guidance literature:

Multi-step reaction with 2 steps

1: dichloromethane / 2 h / 0 °C

2: dimethyl sulfoxide / 1 h / 90 °C

With dimethyl sulfoxide; In dichloromethane;

DOI:10.1016/j.bmcl.2011.11.046

Reference yield:

C12H7NO2 → C26H23N3O6S (1354828-15-1)

Guidance literature:

Multi-step reaction with 8 steps

1: sulfur dioxide; copper dichloride / acetic acid / 20 h / 0 - 20 °C

2: chlorine; acetic acid / water / 8 h / 0 - 20 °C

3: bromine / acetic acid / 6 h / 76 °C

4: N-ethyl-N,N-diisopropylamine / dichloromethane / 18 h / 20 °C

5: tetrakis(triphenylphosphine) palladium⁽⁰⁾ / 1-methyl-pyrrolidin-2-one / 1 h / 120 °C / Microwave irradiation

6: hydroxylamine; triethylamine / 6 h / 20 °C

7: dichloromethane / 2 h / 0 °C

8: dimethyl sulfoxide / 1 h / 90 °C

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sulfur dioxide; hydroxylamine; bromine; chlorine; acetic acid; dimethyl sulfoxide; triethylamine; N-ethyl-N,N-diisopropylamine; copper dichloride; In 1-methyl-pyrrolidin-2-one; dichloromethane; water; acetic acid;

DOI:10.1016/j.bmcl.2011.11.046

Reference yield:

(S)-methyl 2-(8-bromodibenzo[b,d]furan-3-sulfonamido)-3-methylbutanoate (1025720-05-1) → C26H23N3O6S (1354828-15-1)

Guidance literature:

Multi-step reaction with 4 steps

1: tetrakis(triphenylphosphine) palladium⁽⁰⁾ / 1-methyl-pyrrolidin-2-one / 1 h / 120 °C / Microwave irradiation

2: hydroxylamine; triethylamine / 6 h / 20 °C

3: dichloromethane / 2 h / 0 °C

4: dimethyl sulfoxide / 1 h / 90 °C

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; hydroxylamine; dimethyl sulfoxide; triethylamine; In 1-methyl-pyrrolidin-2-one; dichloromethane;

DOI:10.1016/j.bmcl.2011.11.046

upstream raw materials:

8-bromodibenzo[b,d]furan-3-sulfonyl chloride

(S)-methyl 2-(8-bromodibenzo[b,d]furan-3-sulfonamido)-3-methylbutanoate

dibenzofuran

(S)-methyl 2-(8-cyanodibenzo[b,d]furan-3-sulfonamido)-3-methylbutanoate

Downstream raw materials:

(S)-3-methyl-2-(8-(5-phenyl-1,2,4-oxadiazol-3-yl)dibenzo[b,d]furan-3-sulfonamido)butanoic acid