Ethanone, 1-[2-(4-morpholinyl)phenyl]-

Base Information

• Chemical Name: Ethanone, 1-[2-(4-morpholinyl)phenyl]-
• CAS No.: 117607-26-8
• Molecular Formula: C12H15NO2
• Molecular Weight: 205.257
• European Community (EC) Number: 870-133-4
• DSSTox Substance ID: DTXSID80558195
• Wikidata: Q82440397
• Mol file: 117607-26-8.mol

Synonyms:117607-26-8;1-(2-morpholin-4-ylphenyl)ethanone;Ethanone, 1-[2-(4-morpholinyl)phenyl]-;1-[2-(Morpholin-4-yl)phenyl]ethan-1-one;SCHEMBL1286677;DTXSID80558195;RVFFJQBAEALVMC-UHFFFAOYSA-N;AKOS000101310;EN300-82320;G24902;Z111423532

Chemical Property of Ethanone, 1-[2-(4-morpholinyl)phenyl]-

Chemical Property:

• XLogP3: 1.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 205.110278721
• Heavy Atom Count: 15
• Complexity: 224

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)C1=CC=CC=C1N2CCOCC2

Technology Process of Ethanone, 1-[2-(4-morpholinyl)phenyl]-

There total 2 articles about Ethanone, 1-[2-(4-morpholinyl)phenyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

morpholine (110-91-8,99108-56-2) + 2'-Fluoroacetophenone (445-27-2) → 1-<2-(4-morpholinyl)phenyl>ethanone (117607-26-8)

Guidance literature:

In dimethyl sulfoxide; at 115 ℃; for 16h; Inert atmosphere;

DOI:10.1002/ejoc.201301020

Reference yield:

→ 1-<2-(4-morpholinyl)phenyl>ethanone (117607-26-8)

Guidance literature:

Reference yield: 88.0%

1-<2-(4-morpholinyl)phenyl>ethanone (117607-26-8) → 1-(2-morpholinophenyl)ethanol

Guidance literature:

With carbonyl bis(hydrido)tris(triphenylphosphine)ruthenium(II); Butane-1,4-diol; In 1,2-dimethoxyethane; at 115 ℃; for 24h; Inert atmosphere;

DOI:10.1002/ejoc.201301020

upstream raw materials:

morpholine

2'-Fluoroacetophenone

Downstream raw materials:

2-<1-<2-(4-morpholinyl)phenyl>ethylidene>propanedinitrile

2-(2-Hydroxyethylamino)-acetophenon

1-(2-morpholin-4-ylphenyl)ethanone O-methyloxime