4-Benzyloxy-4'-bromo-biphenyl

Base Information

• Chemical Name: 4-Benzyloxy-4'-bromo-biphenyl
• CAS No.: 117692-99-6
• Molecular Formula: C19H15BrO
• Molecular Weight: 339.231
• Hs Code.: 2909309090
• Mol file: 117692-99-6.mol

Synonyms:4-(Benzyloxy)-4'-bromo-1,1'-biphenyl;4-Benzyloxy-4'-bromobiphenyl;

Chemical Property of 4-Benzyloxy-4'-bromo-biphenyl

Chemical Property:

• Boiling Point: 453.6oC at 760 mmHg
• Flash Point: 177.2oC
• PSA: 9.23000
• Density: 1.327g/cm3
• LogP: 5.69510
• Storage Temp.: 2-8°C

Purity/Quality:

98%min ^*data from raw suppliers

4-Benzyloxy-4''-bromobiphenyl ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-Benzyloxy-4'-bromo-biphenyl

There total 1 articles about 4-Benzyloxy-4'-bromo-biphenyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.8%

4-bromo-4'-hydroxybiphenyl (29558-77-8) + benzyl bromide (100-39-0) → 4'-benzyloxy-4-bromobiphenyl (117692-99-6)

Guidance literature:

With potassium carbonate; In butanone; for 6h; Heating / reflux;

Reference yield: 82.0%

4'-benzyloxy-4-bromobiphenyl (117692-99-6) + Diethyl carbonate (105-58-8,76619-83-5) → tris-(4-benzyloxy-biphenyl-4-yl)-methanol (910379-04-3)

Guidance literature:

4'-benzyloxy-4-bromobiphenyl; With n-butyllithium; In tetrahydrofuran; hexane; at -75 ℃; for 2.5h;

Diethyl carbonate; In tetrahydrofuran; hexane; at -75 - 0 ℃;

DOI:10.1002/anie.200600971

Reference yield:

4'-benzyloxy-4-bromobiphenyl (117692-99-6) → 4-[tris-(4'-benzyloxy-biphenyl-4-yl)-methyl]-phenol (910379-07-6)

Guidance literature:

Multi-step reaction with 2 steps

1.1: n-butyllithium / tetrahydrofuran; hexane / 2.5 h / -75 °C

1.2: 82 percent / tetrahydrofuran; hexane / -75 - 0 °C

2.1: 67 percent / HCl / toluene / 8 h / Heating

With hydrogenchloride; n-butyllithium; In tetrahydrofuran; hexane; toluene;

DOI:10.1002/anie.200600971

upstream raw materials:

4-bromo-4'-hydroxybiphenyl

benzyl bromide

Downstream raw materials:

tris-(4-benzyloxy-biphenyl-4-yl)-methanol

4-[tris-(4'-benzyloxy-biphenyl-4-yl)-methyl]-phenol

2-{4-[tris-(4'-benzyloxy-biphenyl-4-yl)-methyl]-phenoxy}-tetrahydro-pyran

Refernces

• 1、 -. "Polymerizable compound, polymerizable resin composition, cured polymer and liquid crystal display device". Page column 41. . Retrieved 2010/02/05.