ethyl 4-[[(1Z)-1-(2-amino-4-oxo-3,5-dihydropyrimido[4,5-b][1,4]oxazin-6-ylidene)-2-ethoxy-2-oxoethyl]amino]benzoate

Base Information

Chemical Name:ethyl 4-[[(1Z)-1-(2-amino-4-oxo-3,5-dihydropyrimido[4,5-b][1,4]oxazin-6-ylidene)-2-ethoxy-2-oxoethyl]amino]benzoate
CAS No.:73217-08-0
Molecular Formula:C₁₉H₂₁N₅O₆
Molecular Weight:415.406
Hs Code.:
NSC Number:342997
DSSTox Substance ID:DTXSID30421608
Wikidata:Q82233177

Synonyms:73217-08-0;AC1O04HU;DTXSID30421608;NSC342997;NSC-342997

Suppliers and Price of ethyl 4-[[(1Z)-1-(2-amino-4-oxo-3,5-dihydropyrimido[4,5-b][1,4]oxazin-6-ylidene)-2-ethoxy-2-oxoethyl]amino]benzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 2 raw suppliers

Chemical Property of ethyl 4-[[(1Z)-1-(2-amino-4-oxo-3,5-dihydropyrimido[4,5-b][1,4]oxazin-6-ylidene)-2-ethoxy-2-oxoethyl]amino]benzoate

Chemical Property:

Density:1.49g/cm³
XLogP3:1
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:8
Exact Mass:415.14918341
Heavy Atom Count:30
Complexity:810

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=CC=C(C=C1)NC(=C2COC3=C(N2)C(=O)NC(=N3)N)C(=O)OCC
Isomeric SMILES:CCOC(=O)C1=CC=C(C=C1)N/C(=C\2/COC3=C(N2)C(=O)NC(=N3)N)/C(=O)OCC

Technology Process of ethyl 4-[[(1Z)-1-(2-amino-4-oxo-3,5-dihydropyrimido[4,5-b][1,4]oxazin-6-ylidene)-2-ethoxy-2-oxoethyl]amino]benzoate

There total 3 articles about ethyl 4-[[(1Z)-1-(2-amino-4-oxo-3,5-dihydropyrimido[4,5-b][1,4]oxazin-6-ylidene)-2-ethoxy-2-oxoethyl]amino]benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 638-07-3
ethyl (2-chloroaceto)acetate

: 73217-08-0
4-{[(2-amino-4-oxo-3,5-dihydro-4H-pyrimido[4,5-b][1,4]oxazin-6-ylidene)-ethoxycarbonyl-methyl]-amino}-benzoic acid ethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: aq. ethanol / Heating

2: Br₂ / acetic acid

3: aq. ethanol / Heating

With bromine; In ethanol; acetic acid;
DOI:10.1002/jhet.5570160733

Reference yield:

: 73217-06-8
(2-amino-4-oxo-3,5-dihydro-4H-pyrimido[4,5-b][1,4]oxazin-6-ylidene)-acetic acid ethyl ester

: 73217-08-0
4-{[(2-amino-4-oxo-3,5-dihydro-4H-pyrimido[4,5-b][1,4]oxazin-6-ylidene)-ethoxycarbonyl-methyl]-amino}-benzoic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: Br₂ / acetic acid

2: aq. ethanol / Heating

With bromine; In ethanol; acetic acid;
DOI:10.1002/jhet.5570160733