Heptanamide, 2,2,3,3,4,4,5,5,6,6,7,7,7-tridecafluoro-N-[4-(1H-tetrazol-5-ylmethyl)phen yl]-

Base Information

• Chemical Name: Heptanamide, 2,2,3,3,4,4,5,5,6,6,7,7,7-tridecafluoro-N-[4-(1H-tetrazol-5-ylmethyl)phen yl]-
• CAS No.: 117897-67-3
• Molecular Formula: C15H8F13N5O
• Molecular Weight: 521.241
• Mol file: 117897-67-3.mol

Synonyms:

Chemical Property of Heptanamide, 2,2,3,3,4,4,5,5,6,6,7,7,7-tridecafluoro-N-[4-(1H-tetrazol-5-ylmethyl)phen yl]-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Heptanamide, 2,2,3,3,4,4,5,5,6,6,7,7,7-tridecafluoro-N-[4-(1H-tetrazol-5-ylmethyl)phen yl]-

There total 5 articles about Heptanamide, 2,2,3,3,4,4,5,5,6,6,7,7,7-tridecafluoro-N-[4-(1H-tetrazol-5-ylmethyl)phen yl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,2,3,3,4,4,5,5,6,6,7,7,7-Tridecafluoro-heptanoic acid (4-cyanomethyl-phenyl)-amide (117897-74-2) → 2,2,3,3,4,4,5,5,6,6,7,7,7-Tridecafluoro-heptanoic acid [4-(1H-tetrazol-5-ylmethyl)-phenyl]-amide (117897-67-3)

Guidance literature:

With sodium azide; ammonium chloride; In N,N-dimethyl-formamide; at 135 ℃;

DOI:10.1021/jm00121a003

Reference yield:

p-aminophenylacetonitrile (3544-25-0) → 2,2,3,3,4,4,5,5,6,6,7,7,7-Tridecafluoro-heptanoic acid [4-(1H-tetrazol-5-ylmethyl)-phenyl]-amide (117897-67-3)

Guidance literature:

Multi-step reaction with 2 steps

1: EtOCCH / ethyl acetate / 15 h / 85 °C

2: NaN₃, NH₄Cl / dimethylformamide / 135 °C

With sodium azide; ammonium chloride; 1-ethoxyacetylene; In ethyl acetate; N,N-dimethyl-formamide;

DOI:10.1021/jm00121a003

Reference yield:

perfluoroheptanoic acid (375-85-9) → 2,2,3,3,4,4,5,5,6,6,7,7,7-Tridecafluoro-heptanoic acid [4-(1H-tetrazol-5-ylmethyl)-phenyl]-amide (117897-67-3)

Guidance literature:

Multi-step reaction with 2 steps

1: EtOCCH / ethyl acetate / 15 h / 85 °C

2: NaN₃, NH₄Cl / dimethylformamide / 135 °C

With sodium azide; ammonium chloride; 1-ethoxyacetylene; In ethyl acetate; N,N-dimethyl-formamide;

DOI:10.1021/jm00121a003

upstream raw materials:

2,2,3,3,4,4,5,5,6,6,7,7,7-Tridecafluoro-heptanoic acid (4-cyanomethyl-phenyl)-amide

p-aminophenylacetonitrile

perfluoroheptanoic acid

perfluoroheptanoyl chloride