375-85-9

Usage

Uses

1. Used in Environmental Applications:
Perfluoroheptanoic acid is used as a persistent environmental pollutant, which can accumulate in human tissues through various exposure routes. It may interfere toxically with the immune system, liver, development, and endocrine systems.
2. Used in Industrial Applications:
Perfluoroheptanoic acid is used as an important organic intermediate in various industries, including agrochemical, pharmaceutical, and dyestuff fields.
3. Used in Consumer Products:
Perfluoroheptanoic acid is used as a component in stainand grease-proof coatings for furniture, carpet, and food packaging.
4. Used in Chemical Research:
Due to its unique chemical properties, Perfluoroheptanoic acid is utilized in chemical research to study the behavior of perfluorinated compounds and their environmental impact.

InChI:InChI=1/C7HF13O2.H3N/c8-2(9,1(21)22)3(10,11)4(12,13)5(14,15)6(16,17)7(18,19)20;/h(H,21,22);1H3

Upstream product

• 626-27-7 n-heptanoic anhydride 
• 559-14-8 perfluorooct-1-ene 
• 111-14-8 oenanthic acid 
• 335-58-0 perfluoroheptyl iodide 
• 96-49-1 [1,3]-dioxolan-2-one 
• 355-43-1 n-perfluorohexyl iodide 
• 124-38-9 carbon dioxide 
• 647-42-7 1H,1H,2H,2H-tridecafluoro-n-octanol 
• 78522-67-5 1,1,2,2,3,3,4,4,4-Nonafluoro-butane-1-sulfonic acid tridecafluorohexyl ester 
• 335-67-1 Perfluorooctanoic acid 
• 335-99-9 2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoro-1-heptanol 
• 1546-95-8 2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoroheptanoic acid 
• 375-84-8 2,2,3,3,4,4,5,5,6,6,7,7,7-tridecafluoroheptanoyl fluoride 
• 52447-22-0 perfluoroheptanoyl chloride 

Downstream Products

• 375-82-6 2,2,3,3,4,4,5,5,6,6,7,7,7-tridecafluoroheptan-1-ol 
• 335-54-6 Perfluorhexanamid 
• 52447-22-0 perfluoroheptanoyl chloride 
• 117897-74-2 2,2,3,3,4,4,5,5,6,6,7,7,7-Tridecafluoro-heptanoic acid (4-cyanomethyl-phenyl)-amide 
• 77893-60-8 tridecafluorohexyl-acetone 
• 136909-77-8 Acetic acid 3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluoro-1-methyl-octyl ester 
• 136909-82-5 Acetic acid 3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluoro-1-methylene-octyl ester 
• 136909-84-7 (Z)-4,5,5,6,6,7,7,8,8,9,9,9-Dodecafluoro-non-3-en-2-one 
• 88950-96-3 2,2,3,3,4,4,5,5,6,6,7,7,7-Tridecafluoro-1-p-tolyl-heptan-1-one 
• 355-37-3 1,1,1,2,2,3,3,4,4,5,5,6,6-tridecafluorohexane 
• 375-84-8 2,2,3,3,4,4,5,5,6,6,7,7,7-tridecafluoroheptanoyl fluoride 
• 119403-54-2 2-(perfluorohexyl)benzimidazole 
• 533-18-6 2-methylphenyl acetate 
• 140-39-6 1-acetoxy-4-methylbenzene 

Relevant academic research and scientific papers

Electrocatalytic degradation of perfluorooctanoic acid by LaNixY1-xO3 (Y = Fe, Cu, Co, Sr) gas dispersion electrode

Perfluorooctanoic acid (PFOA), as a refractory organic pollutant, seriously harms the environment and damages human health. Here, the electrocatalytic method was selected to degrade PFOA. In this work, perovskite catalysts doped with different elements, and corresponding gas diffusion electrodes (GDE) were prepared by the gel-sol method and citric acid complexation method. The crystal structure, microscopic morphology, and electrochemical properties of the LaNixY1-xO3 (Y = Fe, Cu, Co, Sr) perovskite catalyst electrode were analyzed by XRD, TEM, and CV. Moreover, the electrocatalytic performances of the as-prepared electrodes were assessed by the degradation of PFOA, and the Sr-doped GDE exhibited the highest degradation rate of PFOA. The optimum degradation conditions, such as the current density, pH, and initial concentration were also investigated. It was observed that when the current density was 20 mA/cm2, pH was 5, and initial concentration was 0.25 mmol/L, the Sr-doped GDE had the best degradation and defluorination efficiency of PFOA reached 90.0 % and 75.1 %, respectively. High performance liquid chromatography-mass spectrometry (HPLC-MS) was used to analyze the intermediate products of PFOA degradation and obtain the degradation pathway. With the combined action of [rad]OH and O2, PFOA was degraded by stepwise removal of CF2 groups, which were ultimately degraded into F? and CO2.

Preparation method of fluorine-containing carboxylic acid

The invention discloses a preparation method of fluorine-containing carboxylic acid. The method comprises the following steps: reacting fluorine-containing carboxylate used as a raw material with an acylating chlorination reagent to obtain a corresponding mixture of fluorine-containing acyl chloride and fluorine-containing anhydride, and hydrolyzing and drying the mixture of fluorine-containing acyl chloride and fluorine-containing anhydride to obtain high-purity fluorine-containing carboxylic acid. The method provided by the invention is suitable for post-treatment of fluorine-containing carboxylic acid prepared by a fluorine-containing olefin (monoolefine, diene, cycloolefin and the like) oxidation method, replaces the traditional strong acid acidification and ether continuous extractionprocess, and is simpler, more convenient and more applicable; and the method can also be used for recovering and purifying a fluorine-containing carboxylate emulsifier. The purity of the fluorine-containing carboxylic acid prepared by the method can reach 98% or above.

Preparation method of perfluoroheptanoic acid

The invention relates to the technical field of fluorochemical preparation, particularly a preparation method of perfluoroheptanoic acid. The method comprises the following steps: oxidizing dodecafluoroheptanol to obtain dodecafluoroheptanoic acid, carrying out reaction on the dodecafluoroheptanoic acid and thionyl chloride to obtain dodecafluoroheptanoyl chloride, carrying out fluorination on the dodecafluoroheptanoyl chloride to obtain perfluoroheptanoyl chloride, and hydrolyzing to obtain the perfluoroheptanoic acid. The technical process of preparing perfluoroheptanoic acid from dodecafluoroheptanol has the advantages of low energy consumption, no pollution and high yield (up to 75% or above), is easy to operate, and has higher competitive edges than the existing perfluoroheptanoic acid production technique.

The effect of oxygen in the photocatalytic oxidation pathways of perfluorooctanoic acid

The influence of oxygen in the photocatalytic oxidation of perfluorooctanoic acid (PFOA) promoted by a commercial nano-sized titanium dioxide was studied by testing the reaction in different conditions: static air, oxygen flux, nitrogen flux and pre-saturated nitrogen flux. The reaction was monitored by Total Organic Carbon (TOC) analysis and Ionic Chromatography (IC). Shorter chain perfluorocarboxylic acids (PFCAs; Cn, n = 1-7) intermediate degradation products were quantitatively determined by High-Performance Liquid Chromatography combined with Mass Spectrometry (HPLC-MS) analysis. The presence of shorter chain PFCAs in solution was also monitored by 19F NMR. The experimental findings are in agreement with two major oxidative pathways: Cn → Cn-1 photo-redox and β-scissions routes mediated by COF2 elimination. Depending on the experimental conditions, the mutually operating mechanisms could be unbalanced up to the complete predominance of one pathway over the other. In particular, the existence of the β-scissions route with COF2 elimination was corroborated by the isolation and characterization of carbonyl difluoride, a predicted fluorinated decomposition by-product.

A novel liquid plasma AOP device integrating microwaves and ultrasounds and its evaluation in defluorinating perfluorooctanoic acid in aqueous media

A simplified and energy-saving integrated device consisting of a microwave applicator and an ultrasonic homogenizer has been fabricated to generate liquid plasma in a medium possessing high dielectric factors, for example water. The microwave waveguide and the ultrasonic transducer were interconnected through a tungsten/titanium alloy stick acting both as the microwave antenna and as the horn of the ultrasonic homogenizer. Both microwaves and ultrasonic waves are simultaneously transmitted to the aqueous media through the tungsten tip of the antenna. The microwave discharge liquid plasma was easily generated in solution during ultrasonic cavitation. The simple device was evaluated by carrying out the degradation of the perfluorooctanoic acid (PFOA), a system highly recalcitrant to degradation by conventional advanced oxidation processes (AOPs). PFOA is 59% degraded in an aqueous medium after only 90 s of irradiation by the plasma. Intermediates were identified by electrospray mass spectral techniques in the negative ion mode.

Electrochemical and Photocatalytic Decomposition of Perfluorooctanoic acid with a hybrid reactor using a boron-doped diamond electrode and TiO2 photocatalyst

The efficient decomposition of environmentally persistent perfluorooctanoic acid (PFOA) was achieved by a hybrid of electrolysis and photocatalysis. The rate constant of PFOA decomposition in the hybrid system was larger than the sum of the constants in electrolysis-only and photocatalysis-only systems. The hybrid system was able to accelerate the PFOA decomposition by complementally support of two kinds of reaction kinetics. These results could be useful for development of a new continuous system for practical treatment of waste water containing perfluorinated acids.

Efficient mineralization of hydroperfluorocarboxylic acids with persulfate in hot water

The persulfate (S2O82-)-induced decomposition of hydroperfluorocarboxylic acids (H-PFCAs), that is, HCnF2nCOOH (n = 4, 6, and 8), in hot water was investigated, and the results were compared with the

Photocatalytic decomposition of environmentally persistent perfluorooctanoic acid

Perfluorooctanoic acid was photocatalytically decomposed by using TiO 2/Ni-Cu, and a small bias potential (-0.1 V) applied on TiO 2/Ni-Cu electrode greatly enhanced its decomposition. Copyright

Degradation of fluorotelomer alcohols: A likely atmospheric source of perfluorinated carboxylic acids

Human and animal tissues collected in urban and remote global locations contain persistent and bioaccumulative perfluorinated carboxylic acids (PFCAs). The source of PFCAs was previously unknown. Here we present smog chamber studies that indicate fluorotelomer alcohols (FTOHs) can degrade in the atmosphere to yield a homologous series of PFCAs. Atmospheric degradation of FTOHs is likely to contribute to the widespread dissemination of PFCAs. After their bioaccumulation potential is accounted for, the pattern of PFCAs yielded from FTOHs could account for the distinct contamination profile of PFCAs observed in arctic animals. Furthermore, polar bear liver was shown to contain predominately linear isomers (>99%) of perfluorononanoic acid (PFNA), while both branched and linear isomers were observed for perfluorooctanoic acid, strongly suggesting a sole input of PFNA from "telomer"-based products. The significance of the gas-phase peroxy radical cross reactions that produce PFCAs has not been recognized previously. Such reactions are expected to occur during the atmospheric degradation of all polyfluorinated materials, necessitating a reexamination of the environmental fate and impact of this important class of industrial chemicals.

Ozonolysis of alkenes and studies of reactions of polyfunctional compounds: LXV.* Ozonolysis of perfluoro-1-octene in Freon-113

Ozonization of perfluoro-1-octene in Freon-113 yields the corresponding ozonide whose catalytic hydrogenation over Pd/C or hydride reduction leads to formation of perfluoroheptanoic acid; the reduction with lithium aluminum hydride gives 2,2,3,3,4,4,5,5,6,6,7,7,7-tridecafluoro-1-heptanol. Ozonization of perfluoro-1-octene in Freon-113 containing excess (≥3 equiv) alcohol affords the corresponding perfluoroheptanoic acid ester.