4-{4-[(Dimethylamino)methyl]phenyl}cyclohexan-1-one

Base Information

Chemical Name:4-{4-[(Dimethylamino)methyl]phenyl}cyclohexan-1-one
CAS No.:117960-50-6
Molecular Formula:C15H21NO
Molecular Weight:231.338
Hs Code.:
DSSTox Substance ID:DTXSID20572193
Wikidata:Q82460478
Mol file:117960-50-6.mol

Synonyms:117960-50-6;4-{4-[(Dimethylamino)methyl]phenyl}cyclohexan-1-one;SCHEMBL8029561;DTXSID20572193;DLHXNKVFWSWQLA-UHFFFAOYSA-N;4-(4-dimethylaminomethylphenyl)-cyclohexanone

Suppliers and Price of 4-{4-[(Dimethylamino)methyl]phenyl}cyclohexan-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-{4-[(Dimethylamino)methyl]phenyl}cyclohexan-1-one

Chemical Property:

XLogP3:2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:231.162314293
Heavy Atom Count:17
Complexity:244

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)CC1=CC=C(C=C1)C2CCC(=O)CC2

Technology Process of 4-{4-[(Dimethylamino)methyl]phenyl}cyclohexan-1-one

There total 5 articles about 4-{4-[(Dimethylamino)methyl]phenyl}cyclohexan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 117960-53-9
4-(4-Dimethylaminomethyl-phenyl)-cyclohex-3-enone

: 117960-50-6
4-<4-<(dimethylamino)methyl>phenyl>cyclohexanone

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethyl acetate; for 3h; under 760 Torr; Ambient temperature;
DOI:10.1021/jm00122a012

Reference yield:

: 4746-97-8
cyclohexanedione monoethylene ketal

: 117960-50-6
4-<4-<(dimethylamino)methyl>phenyl>cyclohexanone

Guidance literature:: Multi-step reaction with 3 steps

1: 1) Mg / 1) THF, room temperature, ultrasound, 2 h, 2) THF, a) -30 deg C, 1 h, b) room temperature, overnight

2: CF₃COOH / 0.5 h / Ambient temperature

3: H₂ / 10percent Pd/C / ethyl acetate / 3 h / 760 Torr / Ambient temperature

With hydrogen; magnesium; trifluoroacetic acid; palladium on activated charcoal; In ethyl acetate;
DOI:10.1021/jm00122a012

Reference yield:

: 6274-57-3
(4-bromobenzyl)dimethylamine

: 117960-50-6
4-<4-<(dimethylamino)methyl>phenyl>cyclohexanone

Guidance literature:: Multi-step reaction with 3 steps

1: 1) Mg / 1) THF, room temperature, ultrasound, 2 h, 2) THF, a) -30 deg C, 1 h, b) room temperature, overnight

2: CF₃COOH / 0.5 h / Ambient temperature

3: H₂ / 10percent Pd/C / ethyl acetate / 3 h / 760 Torr / Ambient temperature

With hydrogen; magnesium; trifluoroacetic acid; palladium on activated charcoal; In ethyl acetate;
DOI:10.1021/jm00122a012