H-Tz-Bz-NH3Cl hydrochloride

Base Information

Chemical Name:H-Tz-Bz-NH3Cl hydrochloride
CAS No.:1345866-68-3
Molecular Formula:C₉H₉N₅*ClH
Molecular Weight:223.665
Hs Code.:
Mol file:1345866-68-3.mol

Synonyms:

Suppliers and Price of H-Tz-Bz-NH3Cl hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
(4-(1,2,4,5-Tetrazin-3-yl)phenyl)methanamine hydrochloride 95%
25mg
$ 261.00

Sigma-Aldrich
(4-(1,2,4,5-Tetrazin-3-yl)phenyl)methanamine hydrochloride 95%
10mg
$ 112.00

Total 9 raw suppliers

Chemical Property of H-Tz-Bz-NH3Cl hydrochloride

Chemical Property:

Melting Point:206-225°C (decomposition)
Storage Temp.:?20°C
Solubility.:DMSO (Slightly), Methanol (Very Slightly)

Purity/Quality:

98%,99%, ^*data from raw suppliers

(4-(1,2,4,5-Tetrazin-3-yl)phenyl)methanamine hydrochloride 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:T
Statements: 25-36/37/38
Safety Statements: 26-45

MSDS Files:

Useful:

Uses [4-(1,2,4,5-Tetrazin-3-yl)phenyl]methanamine Hydrochloride is a useful reagent in the preparation of tetrazine derivatives and their applications on pyrazolone-based modification of biomolecules.

Technology Process of H-Tz-Bz-NH3Cl hydrochloride

There total 3 articles about H-Tz-Bz-NH3Cl hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1380500-93-5
tert-butyl N-[[4-(1,2,4,5-tetrazin-3-yl)phenyl]methyl]carbamate

: 1345866-68-3,1416711-59-5
r (4-(1,2,4,5-tetrazin-3-yl)phenyl)methanamine hydrochloride

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; at 25 ℃; for 1h; Inert atmosphere;
DOI:10.1021/ja302832g

Reference yield:

: 66389-80-8
tert-butyl N-[(4-cyanophenyl)methyl]carbamate

: 1345866-68-3,1416711-59-5
r (4-(1,2,4,5-tetrazin-3-yl)phenyl)methanamine hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1.1: zinc trifluoromethanesulfonate; hydrazine hydrate / 1,4-dioxane / 16 h / 60 °C / Inert atmosphere

1.2: 0.25 h / 25 °C / Inert atmosphere

2.1: hydrogenchloride / 1,4-dioxane / 1 h / 25 °C / Inert atmosphere

With hydrogenchloride; zinc trifluoromethanesulfonate; hydrazine hydrate; In 1,4-dioxane;
DOI:10.1021/ja302832g

Reference yield:

: 15996-76-6
4-cyanobenzylamine hydrochloride

: 1345866-68-3,1416711-59-5
r (4-(1,2,4,5-tetrazin-3-yl)phenyl)methanamine hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium hydroxide / water / 16 h / 25 °C

2.1: zinc trifluoromethanesulfonate; hydrazine hydrate / 1,4-dioxane / 16 h / 60 °C / Inert atmosphere

2.2: 0.25 h / 25 °C / Inert atmosphere

3.1: hydrogenchloride / 1,4-dioxane / 1 h / 25 °C / Inert atmosphere

With hydrogenchloride; zinc trifluoromethanesulfonate; hydrazine hydrate; sodium hydroxide; In 1,4-dioxane; water;
DOI:10.1021/ja302832g