Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, 3'-(hydrogen phosphonate), compd. with N,N-diethylethanamine (1:1)

Base Information

Chemical Name:Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, 3'-(hydrogen phosphonate), compd. with N,N-diethylethanamine (1:1)
CAS No.:118352-75-3
Molecular Formula:C38H36N5O8P.C6H15N
Molecular Weight:822.898
Hs Code.:

Adenosine,
N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-,
3'-(hydrogen phosphonate), compd. with N,N-diethylethanamine (1:1)

Synonyms:

Suppliers and Price of Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, 3'-(hydrogen phosphonate), compd. with N,N-diethylethanamine (1:1)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, 3'-(hydrogen phosphonate), compd. with N,N-diethylethanamine (1:1)

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, 3'-(hydrogen phosphonate), compd. with N,N-diethylethanamine (1:1)

There total 5 articles about Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, 3'-(hydrogen phosphonate), compd. with N,N-diethylethanamine (1:1) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 64325-78-6
N₆-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine

: 121-44-8
triethylamine

: Ammonium 4-methylphenyl H-phosphonate

: 118352-75-3
Triethylammonium 6-N-benzoyl-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)adenosine 3'-H-phosphonate

Guidance literature:: triethylamine; Ammonium 4-methylphenyl H-phosphonate; With pyridine;

N₆-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine; With pyridine; pivaloyl chloride; at -35 ℃; for 0.5h;

Reference yield: 76.5%

: 64325-78-6
N₆-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine

: 121-44-8
triethylamine

: 118352-75-3
Triethylammonium 6-N-benzoyl-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)adenosine 3'-H-phosphonate

Guidance literature:: With bis(trichloromethyl) carbonate; phosphonic acid; In acetonitrile; for 4h; Ambient temperature;
DOI:10.1016/0040-4039(95)01383-S

Reference yield:

: C₄₅H₄₂N₅O₈P

: 118352-75-3
Triethylammonium 6-N-benzoyl-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)adenosine 3'-H-phosphonate

Guidance literature:: Multi-step reaction with 2 steps

1: H₂O, pyridine / 1 h / Ambient temperature

2: H₂O; CH₂Cl₂ / pH 7.0

With pyridine; water; In dichloromethane; water;
DOI:10.1016/0040-4039(96)01993-4