4,10,12-Tetradecatriene-1,1,8,8-tetracarboxylic acid, 14-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-5-methyl-, tetramethyl ester, (E,Z,E)-

Base Information

• Chemical Name: 4,10,12-Tetradecatriene-1,1,8,8-tetracarboxylic acid, 14-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-5-methyl-, tetramethyl ester, (E,Z,E)-
• CAS No.: 118436-64-9
• Molecular Formula: C39H52O9Si
• Molecular Weight: 692.922
• Mol file: 118436-64-9.mol

Synonyms:

Chemical Property of 4,10,12-Tetradecatriene-1,1,8,8-tetracarboxylic acid, 14-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-5-methyl-, tetramethyl ester, (E,Z,E)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4,10,12-Tetradecatriene-1,1,8,8-tetracarboxylic acid, 14-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-5-methyl-, tetramethyl ester, (E,Z,E)-

There total 50 articles about 4,10,12-Tetradecatriene-1,1,8,8-tetracarboxylic acid, 14-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-5-methyl-, tetramethyl ester, (E,Z,E)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

(5E,11Z,13E)-15-(tert-Butyl-diphenyl-silanyloxy)-9,9-bis-methoxycarbonyl-6-methyl-pentadeca-5,11,13-trienoic acid methyl ester (118427-88-6) + methyl chloroformate (79-22-1) → (5E,11Z,13E)-15-(tert-Butyl-diphenyl-silanyloxy)-2,9,9-tris-methoxycarbonyl-6-methyl-pentadeca-5,11,13-trienoic acid methyl ester (118436-64-9)

Guidance literature:

With lithium diisopropyl amide; In tetrahydrofuran; hexane; at -78 ℃;

Reference yield:

(5E,11E,13E)-15-(tert-Butyl-diphenyl-silanyloxy)-9,9-bis-methoxycarbonyl-6-methyl-pentadeca-5,11,13-trienoic acid methyl ester (118427-88-6) + methyl chloroformate (79-22-1) → (5E,11E,13E)-15-(tert-Butyl-diphenyl-silanyloxy)-2,9,9-tris-methoxycarbonyl-6-methyl-pentadeca-5,11,13-trienoic acid methyl ester (118427-87-5,118436-64-9)

Guidance literature:

With lithium diisopropyl amide; In tetrahydrofuran; at -78 ℃;

DOI:10.1016/S0040-4039(00)82006-7

Reference yield:

(5E,11Z,13Z)-15-(tert-Butyl-diphenyl-silanyloxy)-9,9-bis-methoxycarbonyl-6-methyl-pentadeca-5,11,13-trienoic acid methyl ester (118427-88-6) + methyl chloroformate (79-22-1) → (5E,11Z,13Z)-15-(tert-Butyl-diphenyl-silanyloxy)-2,9,9-tris-methoxycarbonyl-6-methyl-pentadeca-5,11,13-trienoic acid methyl ester (118427-87-5,118436-64-9)

Guidance literature:

With lithium diisopropyl amide; In tetrahydrofuran; at -78 ℃;

DOI:10.1016/S0040-4039(00)82006-7

upstream raw materials:

2-[(2Z,4Z)-6-(tert-Butyl-diphenyl-silanyloxy)-hexa-2,4-dienyl]-2-((Z)-6-methanesulfonyloxy-3-methyl-hex-3-enyl)-malonic acid dimethyl ester

malonic acid dimethyl ester

(Z)-6-(tert-Butyl-dimethyl-silanyloxy)-3-methyl-hex-3-en-1-ol

Methanesulfonic acid (Z)-6-(tert-butyl-dimethyl-silanyloxy)-3-methyl-hex-3-enyl ester