isopropylcyclohexyl(3-hydroxypropoxy)borane

Base Information

• Chemical Name: isopropylcyclohexyl(3-hydroxypropoxy)borane
• CAS No.: 97782-99-5
• Molecular Formula: C₁₂H₂₅BO₂
• Molecular Weight: 212.14
• Mol file: 97782-99-5.mol

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Chemical Property of isopropylcyclohexyl(3-hydroxypropoxy)borane

Chemical Property:

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Technology Process of isopropylcyclohexyl(3-hydroxypropoxy)borane

There total 1 articles about isopropylcyclohexyl(3-hydroxypropoxy)borane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

2-cyclohexyl-1,3,2-dioxaborinane (30169-75-6) + isopropyllithium (1888-75-1) → isopropylcyclohexyl(3-hydroxypropoxy)borane (97782-99-5) + C6H11B(CH(CH3)2)2

Guidance literature:

In diethyl ether; byproducts: LiCl; 1 equiv of i-PrLi slowly adding to a soln. of the boronic ester at -78°C, stirring for 3 h at the same temp., 1 equiv of anhydrous HCl in ether adding, warming to room temp., stirring for 15 min; product content detd. by (11)B NMR spectrum;

DOI:10.1021/om00129a019

upstream raw materials:

2-cyclohexyl-1,3,2-dioxaborinane

isopropyllithium