5-METHYL-2-(TRIBUTYLSTANNYL)FURAN

Base Information

• Chemical Name: 5-METHYL-2-(TRIBUTYLSTANNYL)FURAN
• CAS No.: 118486-95-6
• Molecular Formula: C17H32OSn
• Molecular Weight: 371.15
• Hs Code.: 2932190090
• Mol file: 118486-95-6.mol

Synonyms:tributyl-(5-methylfuran-2-yl)stannane;

Chemical Property of 5-METHYL-2-(TRIBUTYLSTANNYL)FURAN

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 189-190 °C
• Boiling Point: 362.11oC at 760 mmHg
• Flash Point: 172.798oC
• PSA: 13.14000
• LogP: 5.64410

Purity/Quality:

98%,99%, ^*data from raw suppliers

5-Methyl-2-(tributylstannyl)furan ^*data from reagent suppliers

Safty Information:

• Hazard Codes: T

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-METHYL-2-(TRIBUTYLSTANNYL)FURAN

There total 1 articles about 5-METHYL-2-(TRIBUTYLSTANNYL)FURAN which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2-methylfuran (534-22-5) + tributyltin chloride (1461-22-9) → tributyl-(5-methylfuran-2-yl)stannane (118486-95-6)

Guidance literature:

With n-butyllithium; N,N,N,N,-tetramethylethylenediamine; In tetrahydrofuran; hexane; to a stirred THF soln. of the furan and TMEDA n-BuLi in hexane added dropwise (-78°C), stirred (2 h, -40 to -20°C), cooled (-78°C), Bu3SnCl added dropwise (30 min), warmed (room temp.), stirred overnight; quenched (cold water), extracted (ether), washed (satd. NaHCO3), dried (MgSO4), concentrated (vac.), residue passed through a short alumina plug (hexane), solvent removed;

DOI:10.1246/bcsj.65.2366

Reference yield: 98.0%

tributyl-(5-methylfuran-2-yl)stannane (118486-95-6) + ortho-bromobenzaldehyde (6630-33-7) → 2-(5-methylfuran-2-yl)benzaldehyde (400746-82-9)

Guidance literature:

With triphenylphosphine; bis(dibenzylideneacetone)-palladium⁽⁰⁾; In toluene; at 110 ℃; for 3h; Inert atmosphere;

DOI:10.1002/chem.201403113

Reference yield: 91.0%

lead(IV) tetraacetate (546-67-8) + tributyl-(5-methylfuran-2-yl)stannane (118486-95-6) → 5-(acetyloxy)-5-methyl-2(5H)-furanone (74982-59-5)

Guidance literature:

In dichloromethane; for 72h; Ambient temperature;

DOI:10.1246/bcsj.65.2366

upstream raw materials:

2-methylfuran

tributyltin chloride

Downstream raw materials:

5-(acetyloxy)-5-methyl-2(5H)-furanone

protoanemonin

(Sp)-8-(5-methyl-2-furyl)-adenosine-2'O-(tert-butyldimethylsilyl)-3',5'-cyclic N-phenylphosphoramidate

N,N'-bis(2,6-diisopropylphenyl)-1,6,9,13-tetra(5-methylfuran-2-yl)terrylene-3,4:11,12-tetracarboxidiimide

Refernces

• 1、 -. "Adenosine receptor antagonist". Paragraph 0115-0117. . Retrieved 2020/11/09.
• 2、 -. "TETRACENE DERIVATIVE AND METHOD FOR SYNTHESIZING THE SAME, AND ORGANIC ELECTRONICS DEVICE PREPARED USING THE SAME". Paragraph 0092-0094. . Retrieved 2016/10/08.